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ProteomicsA small molecule VDAC ligand inhibits ERAD and induces selective cancer cell death via disruption of calcium homeostasis
Endoplasmic reticulum-associated degradation (ERAD) is a critical protein quality control mechanism that also regulates lipid metabolism and calcium homeostasis. Dysregulation of ERAD and unfolded protein response underlies diseases including cancer, neurodegenerative disorders, and metabolic syndro...
ORGANISM(S): Homo sapiens (Human) 
2026-01-20 | PXD071546 | Pride
Erad Proteomics Ingel digestion Er-phagy Vdac 
UnknownEfficacy and safety of histone deacetylase inhibitors in peripheral T-cell lymphoma: a systematic review and meta-analysis on prospective clinical trials.
Not available
S-EPMC10293743 | biostudies-literature
UnknownTargeting SRSF1 improves cancer immunotherapy by dually acting on CD8<sup>+</sup>T and tumor cells.
Not available
S-EPMC11751439 | biostudies-literature
UnknownPerformance of the London Atlas, Willems, and a new quick method for dental age estimation in Chinese Uyghur children.
Not available
S-EPMC9773604 | biostudies-literature
UnknownTargeting HMGB2 acts as dual immunomodulator by bolstering CD8<sup>+</sup> T cell function and inhibiting tumor growth in hepatocellular carcinoma.
Not available
S-EPMC12047442 | biostudies-literature
UnknownCommunal breeding by women is associated with lower investment from husbands.
Not available
S-EPMC10426074 | biostudies-literature
UnknownEffects of consumer-oriented health information technologies in diabetes management over time: a systematic review and meta-analysis of randomized controlled trials.
Not available
S-EPMC7651962 | biostudies-literature
UnknownPCK1 activates oncogenic autophagy via down-regulation Serine phosphorylation of UBAP2L and antagonizes colorectal cancer growth.
Not available
S-EPMC10105959 | biostudies-literature
UnknownDiscovery of a novel IL-15 based protein with improved developability and efficacy for cancer immunotherapy.
Not available
S-EPMC5955975 | biostudies-literature
TranscriptomicsRegulatory role of SrrAB two-component system in Staphylococcus epidermidis growth and biofilm formation
Biofilm formation is considered the most important factor involved in pathogenicity of Staphylococcus epidermidis.We investigated the role of two-component signal transduction system (TCS) srrAB, which was up-regulated under micro-aerobic condition, in the growth and biofilm formation of S. epidermi...
ORGANISM(S): Staphylococcus epidermidis 
2014-11-21 | E-GEOD-47101 | biostudies-arrayexpress
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