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ProteomicsMIRO-1 interacts with VDAC-1 to regulate mitochondrial membrane potential in Caenorhabditis elegans
Precise regulation of mitochondrial fusion and fission is essential for cellular activity and animal development. Imbalances between these processes can lead to fragmentation and loss of normal membrane potential in individual mitochondria. In this study, we show that MIRO-1 is stochastically elevat...
ORGANISM(S): Caenorhabditis Elegans 
2023-05-10 | PXD040748 |
UnknownHuman VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia.
Not available
S-EPMC10286422 | biostudies-literature
UnknownAlpha-Synuclein and Mitochondrial Dysfunction in Parkinson's Disease: The Emerging Role of VDAC.
Not available
S-EPMC8170894 | biostudies-literature
ProteomicsA small molecule VDAC ligand inhibits ERAD and induces selective cancer cell death via disruption of calcium homeostasis
Endoplasmic reticulum-associated degradation (ERAD) is a critical protein quality control mechanism that also regulates lipid metabolism and calcium homeostasis. Dysregulation of ERAD and unfolded protein response underlies diseases including cancer, neurodegenerative disorders, and metabolic syndro...
ORGANISM(S): Homo sapiens (Human) 
2026-01-20 | PXD071546 | Pride
Erad Proteomics Ingel digestion Er-phagy Vdac 
UnknownATP transport through VDAC and the VDAC-tubulin complex probed by equilibrium and nonequilibrium MD simulations.
Not available
S-EPMC7259721 | biostudies-literature
ProteomicsProteomic shifts reflecting oxidative stress and reduced capacity for protein synthesis, and alterations to mitochondrial membranes in Neurospora crassa lacking VDAC
Proteomic analysis of N. crassa was performed to explore the role of VDAC (voltage dependent anion-selective channels) in the regulation of cellular processes. Differential label free quantitation was applied to both wild-type and VDAC-knockout versions, involving both cytosolic and mitochondrial i...
ORGANISM(S): Neurospora Crassa (ncbitaxon:5141) 
2021-12-14 | MSV000088567 | MassIVE
UnknownThe role of lipids in VDAC oligomerization.
Not available
S-EPMC3274789 | biostudies-literature
ProteomicsStructure of human PINK1 at a mitochondrial TOM/VDAC array
We report here the structure of human PINK1 stabilized mid-import at an array of endogenous TOM and VDAC complexes purified from human mitochondria. In our structure, two TOM core complexes are separated by a dimer of VDAC2 channels, and an inactive PINK1 dimer is inserted into the VDAC-proximal TOM...
ORGANISM(S): Homo sapiens (Human) 
2025-05-05 | PXD058529 | Pride
Pink1 Cryoem Xl-ms Parkinson's diseease 
UnknownModulation of plant mitochondrial VDAC by phytosterols.
Not available
S-EPMC3042562 | biostudies-literature
UnknownVDAC Genes Expression and Regulation in Mammals.
Not available
S-EPMC8374620 | biostudies-literature
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