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ProteomicsGlobal Stability Profling of Colorectal Cancer Chemoresistance
Almost half of the patients with advanced colorectal cancer (CRC) are resistant to oxaliplatin based therapy, the first line treatment for CRC. Therefore, predicting and understanding oxaliplatin resistance is important to improve CRC patient survival. Investigated here is the use of proteomic foldi...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-04-28 | PXD036298 | Pride
Colorectal cancer Oxaliplatin Sprox Tpp Lip 
ProteomicsOne-pot analysis on cyclosporine A binding
Investigate if one-pot analysis works on several energetic-based proteomics method on cyclosporine A.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-08 | PXD014309 | Pride
Yeast Stepp Sprox Tpp Cpp One-pot 
ProteomicsClemastine Fumarate in Plasmodium
The binding target for clemastine fumarate in Plasmodium Falciparum 3D7 strain is identified by two techniques: SPROX and TPP.
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum (isolate 3D7) 
2020-02-21 | PXD014308 | Pride
Clemastine fumarate Anti-malarial Plasmodium 
ProteomicsQuantitative profiling of STOichiometry by Resolvable Mass tags
Post-translational modifications (PTMs) play important roles in modulating biological functions of proteins. Stoichiometry, which quantifies the modification percentage, is a critical factor for any given PTM. In this work, we developed a chemoproteomic strategy called “STO-MS” to systematically qua...
ORGANISM(S): Homo Sapiens 
2024-10-08 | PXD056632 |
ProteomicsSingle cell analysis for oocytes and early embryos
While non-mammalian embryos often rely on spatial pre-patterning, for decades it was believed that blastomeres of mouse and human embryos were developmentally equivalent. However, emerging evidence suggests early mouse and human blastomeres differ in developmental potential. Here, using multiplexed ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2025-08-10 | MSV000098778 | MassIVE
ProteomicsProteome asymmetry in mouse and human embryos before fate specification
Raw files of early-stage mouse and human blastomeres & mouse zygotes
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2022-05-02 | MSV000089353 | MassIVE
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