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TFIIH is a 10-protein complex that is conserved throughout eukaryotes. TFIIH has two primary cellular functions: transcription initiation and nucleotide excision repair (NER). NER in eukaryotes begins by recognition of a bulky lesion by the obligate dimer Rad4-Rad23. This is followed closely by the ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-07-07 | PXD021212 | Pride
The Rad23/Rad4 protein complex plays a major role in DNA damage recognition during nucleotide excision repair (NER) in yeast. We recently showed that two distinct pathways contribute to efficient NER in yeast. The first operates independently of de novo protein synthesis and requires a nonproteolyti...
ORGANISM(S): Saccharomyces cerevisiae 
The Rad23/Rad4 protein complex plays a major role in DNA damage recognition during nucleotide excision repair (NER) in yeast. We recently showed that two distinct pathways contribute to efficient NER in yeast. The first operates independently of de novo protein synthesis and requires a nonproteolyti...
ORGANISM(S): Saccharomyces cerevisiae 
2010-08-02 | GSE23204 | GEO
The Rad23/Rad4 protein complex plays a major role in DNA damage recognition during nucleotide excision repair (NER) in yeast. We recently showed that two distinct pathways contribute to efficient NER in yeast. The first operates independently of de novo protein synthesis and requires a nonproteolyti...
ORGANISM(S): Saccharomyces cerevisiae 
The Rad23/Rad4 protein complex plays a major role in DNA damage recognition during nucleotide excision repair (NER) in yeast. We recently showed that two distinct pathways contribute to efficient NER in yeast. The first operates independently of de novo protein synthesis and requires a nonproteolyti...
ORGANISM(S): Saccharomyces cerevisiae 
2009-06-01 | GSE11871 | GEO
The Role of the Rad4-Rad23 Complex and Rad4 Ubiquitination in UV-Responsive Transcription
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