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ProteomicsTandem affinity purification coupled with mass spectrometry (TAP-MS) to identify the proteins that interact with RAD51, RAD51 paralogs (RAD51B, RAD51C,RAD51D,XRCC2 and XRCC3), PFKP and PFKP-F649L in HeLa cells.
Tandem affinity purification coupled with mass spectrometry (TAP-MS) was used to identify the proteins that interact with RAD51,RAD51 paralogs (RAD51B, RAD51C,RAD51D,XRCC2 and XRCC3),PFKP and PFKP-F649L in HeLa cells. In addition, we also investigated the phosphorylation of RAD51.
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD070095 | Pride
Rad51paralogs Rad51 Pfkp-f649l Hela cells Rad51 phosphorylation Pfkp 
ProteomicsInhibition of nuclear PTEN tyrosine phosphorylation enhances glioma radiation sensitivity through attenuated DNA repair
Glioblastoma (GBM) is the most lethal brain tumour that occurs in adults and treatment for GBM has been largely unsuccessful. Ionizing radiation (IR) and chemotherapeutic agents are employed as standard of care treatment for GBM patients and both result in DNA damage. Previous data identified phosph...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-07 | MSV000081423 | MassIVE
GenomicsAcetylation of histone H4 at lysine 44 facilitates meiotic recombination by creating accessible chromatin [ChIP-seq]
Meiotic recombination hotspots are associated with histone post-translational modifications and open chromatin. However, it remains unclear how histone modifications and chromatin structure directly regulate meiotic recombination. Here, we identify acetylation of histone H4 at Lys44 (H4K44ac) as a n...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-07 | E-GEOD-59003 | biostudies-arrayexpress
UnknownRegulation of Rad51 function by phosphorylation.
Not available
S-EPMC3147262 | biostudies-literature
UnknownMek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1.
Not available
S-EPMC4970670 | biostudies-literature
UnknownA phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination.
Not available
S-EPMC5204351 | biostudies-literature
UnknownATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 function.
Not available
S-EPMC5341514 | biostudies-literature
UnknownCyclin D1 promotes BRCA2-Rad51 interaction by restricting cyclin A/B-dependent BRCA2 phosphorylation.
Not available
S-EPMC6538526 | biostudies-literature
UnknownNew Phosphorylation Sites of Rad51 by c-Met Modulates Presynaptic Filament Stability.
Not available
S-EPMC6468871 | biostudies-literature
UnknownCDK phosphorylation of Sfr1 downregulates Rad51 function in late-meiotic homolog invasions.
Not available
S-EPMC11445502 | biostudies-literature
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