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UnknownVirtual screening of phytochemical compounds as potential inhibitors against SARS-CoV-2 infection.
Not available
S-EPMC7841026 | biostudies-literature
GenomicsRetrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells (RNA-seq)
Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells (RNA-seq)
PRJNA942617 | ENA
GenomicsRetrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells (scRNA-Seq)
Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells (scRNA-Seq)
PRJNA943421 | ENA
GenomicsclampFISH 2.0 enables rapid, scalable amplified RNA detection in situ
clampFISH 2.0 enables rapid, scalable amplified RNA detection in situ
PRJNA870496 | ENA
TranscriptomicsLocalization and Abundance Analysis of Human lncRNAs at Single Cell and Single Molecule Resolution
Long noncoding RNAs (lncRNAs) have emerged as key players in different cellular processes and are required for diverse functions in vivo. However, fundamental aspects of lncRNA biology remain poorly characterized, including their subcellular localization, abundance and variation at a single cell res...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-57049 | biostudies-arrayexpress
TranscriptomicsSingle cell differences in matrix gene expression do not predict matrix deposition
We performed RNA sequencing on several clones of bovine mesenchymal stem cells from the same donor. Bulk mRNA sequencing in 17 different clones from the same donor and a heterogeneous population from the same donor.
ORGANISM(S): Bos taurus 
2016-01-18 | E-GEOD-76881 | biostudies-arrayexpress
TranscriptomicsSingle mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms
We performed single-cell and bulk transcriptome profiling in two different human cell lines. We performed single-cell RNA sequencing in live and fixed cells. Single cell RNA sequencing of live and fixed cells, bulk RNA sequencing in two cell lines.
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-66053 | biostudies-arrayexpress
TranscriptomicsTrans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation
Long noncoding RNAs (lncRNAs) have emerged as an important layer of genome regulation with common mechanistic themes including the formation of ribonucleoprotein complexes. Here, we present a novel X-linked lncRNA termed linc-Firre that escapes X-chromosome inactivation and forms trans-chromosomal i...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-45157 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of RNA secondary structure conservation between two metazoans
The secondary structure of RNA is necessary for its maturation, regulation, and processing. However, the global influence of RNA folding in eukaryotes is still unclear. Here, we identify evolutionarily conserved features of RNA secondary structure in metazoans by applying our high-throughput, sequen...
ORGANISM(S): Caenorhabditis elegans 
2012-01-26 | E-GEOD-29571 | biostudies-arrayexpress
TranscriptomicsControl of Somatic Tissue Differentiation by the Long Non-Coding RNA TINCR (array)
Several of the thousands of human long non-coding RNAs (lncRNAs) have been functionally characterized; however, potential roles for lncRNAs in somatic tissue differentiation remain poorly understood. Here we show that a 3.7kb lncRNA, terminal differentiation-induced ncRNA (TINCR), controls human ...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-40122 | biostudies-arrayexpress
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