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TranscriptomicsSparse feature selection methods identify unexpected global cellular response to strontium-containing materials
Despite the increasing sophistication of biomaterials design and functional characterization studies, little is known regarding cells' global response to biomaterials. Here, we combined nontargeted holistic biological and physical science techniques to evaluate how simple strontium ion incorporation...
ORGANISM(S): Homo sapiens 
2018-11-25 | E-MTAB-7384 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of Clostridium thermocellum ATCC 27405 cellulose fermentation
Background: The ability of Clostridium thermocellum ATCC 27405 wild-type strain to hydrolyze cellulose and ferment the degradation products directly to ethanol and other metabolic byproducts makes it an attractive candidate for consolidated bioprocessing of cellulosic biomass to biofuels. In this st...
ORGANISM(S): Clostridium thermocellum ATCC 27405 
2011-05-27 | E-GEOD-29554 | biostudies-arrayexpress
TranscriptomicsQuality Control in Microarray Assessment of Gene Expression in Human Airway Epithelium
Microarray technology provides a powerful tool for defining gene expression profiles of airway epithelium that lend insight into the pathogenesis of human airway disorders. The focus of this study was to establish rigorous quality control parameters to ensure that microarray assessment of the airway...
ORGANISM(S): Homo sapiens 
2010-09-19 | E-GEOD-11906 | biostudies-arrayexpress
TranscriptomicsBiologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking
The first changes associated with smoking are in the small airway epithelium (SAE). Given that smoking alters SAE gene expression, but only a fraction of smokers develop chronic obstructive pulmonary disease (COPD), we hypothesized that assessment of SAE genome-wide gene expression would permit biol...
ORGANISM(S): Homo sapiens 
2011-10-26 | E-GEOD-11784 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 1019 human cancer cell lines from the Cancer Cell Line Encyclopedia
RNA-seq of 1019 human cancer cell lines from the Broad-Novartis Cancer Cell Line Encyclopedia (http://www.broadinstitute.org/ccle). The original annotation of each cell line to a disease has been checked and manually curated by Expression Atlas (https://www.ebi.ac.uk/gxa/home). Note the original ver...
ORGANISM(S): Homo sapiens 
2013-05-31 | E-MTAB-2770 | biostudies-arrayexpress
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