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TranscriptomicsMicroRNAs regulate DC maturation via M-CSFR
We identify a panel of microRNAs that are differentially expressed during both spontaneous and LPS-induced DC maturation and show the M-CSF receptor (M-CSFR) as a key target for microRNA-mediated regulation. MicroRNA-22, -34a and -155 are up-regulated in mature GM-CSF-generated DC and mediate M-CSFR...
ORGANISM(S): Mus musculus 
2013-11-04 | E-MEXP-3311 | biostudies-arrayexpress
MetabolomicsSystemic Inflammation Induces Cholestasis via Upregulating a Short Variant of FTO to Remove the m6A Methylation in the 3’-UTR of Cyp7b1 mRNAs in liver
The cholestasis frequently occurs in patients with inflammatory processes. However, the mechanisms of inflammation in inducing cholestasis are still unclear. Here, by using lipopolysaccharide (LPS)-induced cholestasis mouse models, we found that most genes encoding enzymes responsible for bile acid ...
2025-11-07 | MTBLS10713 | MetaboLights
TranscriptomicsTranscriptomic profiling of Salmonella during lag, exponential and stationary phases of growth
Transcriptional profiles during all phases of growth of Salmonella Typhimurium SL1344 were obtained and used to investigate growth phase-dependent alterations in gene expression. Viable count growth curve analysis of the growth system showed a culture lag time of 2.09 hours, and profiles at 4, 20, 4...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2011-12-13 | E-GEOD-22294 | biostudies-arrayexpress
Proteomicsran asters proteomics - Proteomic profiling of microtubule self-organization in M-phase
The main proteomics events driving the self-organization of MTs in M-phase cytoplasms are determined by obtaining the full proteomes of the RanGTP induced MT structures at different time points in Xenopus egg extracts.
ORGANISM(S): Xenopus laevis (African clawed frog) 
2018-07-11 | PXD008306 | Pride
Ran asters proteomics 
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
ProteomicsThe nucleoporin Nup50 activates the Ran guanyl-nucleotide exchange factor RCC1 to promote NPC assembly at the end of mitosis
During mitotic exit, thousands of nuclear pore complexes (NPCs) assemble concomitant with the nuclear envelope to build a transport-competent nucleus. Here, we show that Nup50 plays a crucial role in NPC assembly independent of its well-established function in nuclear transport. RNAi-mediated downre...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD028701 | Pride
Ap-ms Nuclear pore complex Xenopus 
UnknownDepolymerization of vulcanized poly(cyclopentene), poly(norbornene-<i>ran</i>-cyclopentene) and poly(<i>endo</i>-dicyclopentadiene-<i>ran</i>-cyclopentene) rubbers <i>via</i> ring-closing metathesis depolymerization for monomer recycling.
Not available
S-EPMC11577345 | biostudies-literature
UnknownA 7-min halftime jog mitigated the reduction in sprint performance for the initial 15-min of the second half in a simulated football match.
Not available
S-EPMC9295982 | biostudies-literature
TranscriptomicsTemporal response of DCs to LPS stimulation: 4sU_sequencing
Regulation of RNA levels is critical for the response to external stimuli and determined through the interplay between RNA production, processing and degradation. Despite the centrality of these processes, most global studies of RNA regulation do not distinguish their separate contributions and rela...
ORGANISM(S): Mus musculus 
2011-04-24 | E-GEOD-25432 | biostudies-arrayexpress
TranscriptomicsMaternal Plane Of Nutrition During Late Gestation And Weaning Age Alter Offspring Transcriptome Profiles Of Longissimus Muscle In Angus M-CM-^W Simmental
We evaluated if a higher plane of maternal nutrition during late gestation and weaning age alters the offspringM-bM-^@M-^Ys Longissimus muscle (LM) transcriptome. A microarray analysis was performed in LM samples of early (EW) and normal weaned (NW) Angus M-CM-^W Simmental calves born from cows that...
ORGANISM(S): Bos taurus 
2015-02-03 | E-GEOD-65560 | biostudies-arrayexpress
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