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ProteomicsRAN, TDP43 and G3BP1 mRNA form a complex
To identify the candidate that directly stabilizes G3BP1 mRNA, the enriched proteins pulled down by G3BP1 probes and anti-RAN antibody were subjected to mass spectrometry (MS) analysis
ORGANISM(S): Homo Sapiens 
PXD056577 |
GenomicsWGS for B16-OVA and 4T1 murine cancer cell lines
Whole Genome Sequencing of the murine breast cancer cell line 4T1 and of the murine melanoma cell line B16-ova was carried out with the aim of identifying somatic mutations. We also ran deep Mass Spectrometry proteomics analysis on the same cell lines, aiming to determine which somatic mutations car...
ORGANISM(S): Mus musculus 
2024-01-31 | E-MTAB-13635 | biostudies-arrayexpress
GenomicsOpen chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Dnase-Seq]
The epithelium lining the epididymis in the male reproductive tract maintains a luminal environment that promotes sperm cell maturation. This process is dependent on the coordinated expression of many genes that encode proteins with a role in epithelial transport. We previously generated genome-wide...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-59782 | biostudies-arrayexpress
TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
TranscriptomicsOpen chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq]
The epithelium lining the epididymis in the male reproductive tract maintains a luminal environment that promotes sperm cell maturation. This process is dependent on the coordinated expression of many genes that encode proteins with a role in epithelial transport. We previously generated genome-wide...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-59781 | biostudies-arrayexpress
TranscriptomicsOpen chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Agilent expression]
The epithelium lining the epididymis in the male reproductive tract maintains a luminal environment that promotes sperm cell maturation. This process is dependent on the coordinated expression of many genes that encode proteins with a role in epithelial transport. We previously generated genome-wide...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-60381 | biostudies-arrayexpress
UnknownDeep Neural Networks Offer Morphologic Classification and Diagnosis of Bacterial Vaginosis.
Not available
S-EPMC8111127 | biostudies-literature
TranscriptomicsPorcine spleen_Haemophilus Parasuis infected_7days
Haemophilus parasuis(HPS) is a prominent swine pathogen that causes GlM-CM-$sser's disease characterized by fibrinous polyserositis, meningitis and arthritis; however, the molecular mechanisms underlying disease pathogenesis remains poorly understood, particularly the host counteraction to HPS invas...
ORGANISM(S): Sus scrofa 
2009-03-26 | E-GEOD-11787 | biostudies-arrayexpress
ProteomicsRNA MS2-tag based affinity method was used to purify 3' processing factors associated with intronic PAS processing
three copies of the MS2 hairpin were fused to the intronic PAS of the nr3c1 gene. To make a negative control RNA substrate, the core hexamer AAUAAA within PAS was mutated to AACAAA. Subsequently, the RNA substrate was incubated with HeLa NE, and the mRNA 3' processing complex was purified using an M...
ORGANISM(S): Homo Sapiens 
2023-02-27 | PXD040405 |
ProteomicsTandem mass tagging (TMT) proteomics analysis of myocardium from 3 septic mice and 3 normal controls
Sepsis is often a cause of mortality in patients admitted to the intensive care unit. Notably, the heart is the organ most susceptible to the impact of sepsis.Mice injected intraperitoneally with LPS solution (20 mg/kg) were designated as the sepsis experimental group, while those injected intraperi...
ORGANISM(S): Mus Musculus 
2025-01-07 | PXD059523 |
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