Sort   by:  
 Page size 
TranscriptomicsSex-related differences in gene expression following Coxiella burnetii infection: potential role of circadian rhythm
Q fever, a zoonosis due to Coxiella burnetii infection, exhibits sexual dimorphism; men are affected more frequently and severely than women for a given exposure. Here we explore whether the severity of C. burnetii infection in mice is related to differences in male and female gene expression profil...
ORGANISM(S): Mus musculus 
2010-10-02 | E-GEOD-21065 | biostudies-arrayexpress
TranscriptomicsGene Expression Analysis of Blood Reveals S100A11 and AQP9 as Potential Biomarkers of Infective Endocarditis
BackgroundM-bM-^@M-^TDiagnosis and pronostic assessment are challenging in infective endocarditis (IE). To investigate the host response during IE and identify potential biomarkers, we determined the circulating gene expression profile through a whole genome microarray analysis. Methods and ResultsM...
ORGANISM(S): Homo sapiens 
2012-03-12 | E-GEOD-29161 | biostudies-arrayexpress
TranscriptomicsToxin-antitoxin of Rickettsia determines fatal addiction of the host cells
Rickettsia spp. can cause mild to severe human disease. These intracellular bacteria are associated with arthropods, nematodes and trematodes, and usually, are efficiently transmitted transovarially to the progeny of the invertebrate host. We recently demonstrated foreign gene acquisition by lateral...
ORGANISM(S): Homo sapiens 
2012-05-23 | E-GEOD-22072 | biostudies-arrayexpress
TranscriptomicsR. conorii transcriptional response within inoculation eschar battlefield
Rickettsia conorii, the causative agent of the MSF is transmitted to humans by the bite of infected ticks Rhipicephalus sanguineus. The skin thus constitutes an important barrier for the entry and propagation of R. conorii. Given this, analysis of the survival strategies used by the bacterium within...
ORGANISM(S): Rickettsia conorii 
2008-11-06 | E-GEOD-12130 | biostudies-arrayexpress
TranscriptomicsGenotyping of Coxiella burnetii strains collection
Genotyping based on genomic comparative hybridization of different isolates of coxiella burnetii compared to NMI reference strain Two-condition experiment, NMI vs. isolates. One replicate per isolate.
ORGANISM(S): Coxiella burnetii 
2011-12-31 | E-GEOD-31543 | biostudies-arrayexpress
TranscriptomicsEarly response of Coxiella burnetii to temperature stress
Transcriptional profiling of Coxiella burnetii phase I (RSA 493) submitting either to Cold and Heat shock comparing to control untreated Coxiella burnetii phase I (RSA 493) grown at 35°C. Four experiments : Cold shock 30 min Vs 35°C; Cold shock 60 min Vs 35°C; Heat shock 30 min Vs 35°C; Heat sho...
ORGANISM(S): Coxiella burnetii 
2011-01-01 | E-GEOD-21778 | biostudies-arrayexpress
TranscriptomicsGranulomatous response to Coxiella burnetii, the agent of Q fever: Activation of type I interferon-related genes
The formation of granulomas is associated with the resolution of Q fever, a zoonosis due to Coxiella burnetii; however the molecular mechanisms of granuloma formation remain poorly understood. We generated human granulomas with peripheral blood mononuclear cells and beads coated with C. burnetii, us...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-37666 | biostudies-arrayexpress
TranscriptomicsDevelopment and validation of a microarray for the investigation of the CAZymes encoded by the human gut microbiome
Distal gut bacteria play a pivotal role in the digestion of dietary polysaccharides by producing a large number of carbohydrate-active enzymes (CAZymes) that the host otherwise does not produce. We report here the design of a high density custom microarray that we used to spot non-redundant DNA prob...
ORGANISM(S): human gut metagenome 
2013-10-28 | E-GEOD-51760 | biostudies-arrayexpress
TranscriptomicsEvaluation of the effects of Lactobacillus sp. (ostrich) on body weight, the intestinal microbiome and metabolism in mice
Background. Food can affect the microbial balance in the human intestine, and the ingestion of probiotics may play a role in the current obesity pandemic. The objective of our study was to determine if increased Lactobacillus spp. in the intestinal microflora of mice can promote growth and if change...
ORGANISM(S): Mus musculus 
2010-09-21 | E-GEOD-24219 | biostudies-arrayexpress
UnknownRare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.
Not available
S-EPMC10074346 | biostudies-literature
Sort   by:  
 Page size