Sort   by:  
 Page size 
ProteomicsIdentifying RasGAP SH2 binding partners in Drosophila using mass spectrometry
Drosophila S2 cells were transfected with RasGAP(WT), RasGAP(SH2*32*) and GFP control. 4 mg of S2 cell lysate was used to pulldown LAP and GFP tagged constructs using GFP-Trap. The pulled down fraction was loaded on SDS-PAGE gels and coomassie stained before several bands (a-u) from two independent ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2014-05-20 | PXD000176 | Pride
Sh2 Rasgap Schneider 2 (s2) cells Drosophila 
ProteomicsE. coli acquires specific resistance to the antimicrobial peptide TAT-RasGAP (317-326) via modification of charge at the surface of the essential outer membrane insertase BamA
Antimicrobial peptides (AMPs) are promising alternatives to classical antibiotics against multidrug resistant pathogens. TAT-RasGAP (317-326) is an AMP with broad range antibacterial activity, but its mechanism of action is unknown. Escherichia coli can become partially resistant to TAT-RasGAP (317-...
ORGANISM(S): Escherichia coli 
2024-12-02 | PXD051962 | Pride
Resistance Antimicrobial peptides Outer membrane Gram-negative bacteria 
UnknownRevisiting G3BP1 as a RasGAP binding protein: sensitization of tumor cells to chemotherapy by the RasGAP 317-326 sequence does not involve G3BP1.
Not available
S-EPMC3242762 | biostudies-literature
UnknownRASAL3 Is a Putative RasGAP Modulating Inflammatory Response by Neutrophils.
Not available
S-EPMC8579101 | biostudies-literature
UnknownThe NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling.
Not available
S-EPMC6756068 | biostudies-literature
UnknownControl of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein.
Not available
S-EPMC83986 | biostudies-literature
UnknownClinically observed <i>RASA1</i> missense mutants exhibit diverse RasGAP protein behaviors.
Not available
S-EPMC12621883 | biostudies-literature
UnknownPartial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions.
Not available
S-EPMC529026 | biostudies-literature
Unknownp120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP.
Not available
S-EPMC10809936 | biostudies-literature
TranscriptomicsPRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies [expression array]
The polycomb repressive complex 2 (PRC2) exerts oncogenic effects in many tumour types1. However, loss-of-function mutations in PRC2 components occur in a subset of haematopoietic malignancies, sug- gesting that this complex plays a dichotomous and poorly understood role in cancer2,3. Here we provid...
ORGANISM(S): Homo sapiens 
2014-10-21 | E-GEOD-62500 | biostudies-arrayexpress
Sort   by:  
 Page size