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GenomicsShewanella sp. HL-SH2
Shewanella sp. HL-SH2 Genome sequencing
PRJNA1273589 | ENA
GenomicsVibrio parahaemolyticus strain:SH2-1 | isolate:SH2-1
Vibrio parahaemolyticus strain:SH2-1 | isolate:SH2-1 Genome sequencing and assembly
PRJNA915725 | ENA
GenomicsVibrio parahaemolyticus strain:SH2-2 | isolate:SH2-2
Vibrio parahaemolyticus strain:SH2-2 | isolate:SH2-2 Genome sequencing and assembly
PRJNA915726 | ENA
ProteomicsEngineering human SH2 domains for targeted phospho-proteomics
A comprehensive analysis of the phosphoproteome is essential for understanding molecular mechanisms of human diseases. However, current tools to enrich phosphotyrosine are limited in their applicability and scope. Here, we engineered new superbinder SH2 domains that enrich diverse sets of phosphotyr...
ORGANISM(S): Homo sapiens (Human) 
2023-01-13 | PXD030038 | Pride
Phosphoproteomics Synthetic biology K562 Src homology 2 domains Sh2 superbinders Mass spectrometry Human Structural biology Protein engineering Phosphotyrosine 
GenomicsZea mays cultivar:Ia453-sh2
Transcriptome of endosperm of Zea mays Ia453-sh2
PRJNA647735 | ENA
GenomicsZea mays cultivar:Ia453-sh2
Zea mays Ia453-sh2 Transcriptome of endosperm
PRJNA647770 | ENA
ProteomicsA sensitive and cost-effective approach for tyrosine phosphoproteome analysis based on SH2 superbinder
Albeit much less abundant than Ser/Thr phosphorylation (pSer/pThr), Tyr phosphorylation (pTyr) is considered a hallmark in cellular signal transduction. However, its analysis remains a challenge. The conventional immunopurification (IP) approach using antibodies pan-specific to pTyr sites is known t...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-08-29 | PXD005838 | Pride
Lc ms/ms Sh2 superbinder Ptyr phosphoproteome 
TranscriptomicsTranscription profiling of rat PC12 cells stably transfected with GFP, GFP-SH2-Bb, or GFP-SH2-Bb(R555E), treated with or without NGF for 6h
Expression profiling of PC12 cells stably transfected with GFP, GFP-SH2-Bb, or GFP-SH2-Bb(R555E), treated with or without NGF for 6h Experiment Overall Design: Total RNA was obtained from PC12 cells Experiment Overall Design: -stably transfected with GFP (G0) Experiment Overall Design: -stably trans...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-4557 | biostudies-arrayexpress
TranscriptomicsA Dictyostelium SH2 domain adaptor protein required for correct DIF-1 signaling and pattern formation
When developing in the light slug formation in LrrB null (lrrB-) mutants is delayed, relative to the parental strain, and the slugs are highly defective in phototaxis and thermotaxis. In the dark the mutant arrests development as an elongated mound, in a novel process we term dark stalling. The deve...
ORGANISM(S): Dictyostelium discoideum 
2011-05-31 | E-TABM-1090 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis SH2 domain-containing gene PASTA mutant vs. wild type
The protein modules known as SH2 (Src-homology-2) domains are key players in the signal transduction of animals. Two questions arise: Do such modules exist in plants, and when did SH2 domains evolve? Here I show that the Arabidopsis genome contains three strong candidates for plant SH2 proteins (ref...
ORGANISM(S): Arabidopsis thaliana 
2008-06-13 | E-GEOD-5619 | biostudies-arrayexpress
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