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TranscriptomicsTranscription profiling of mouse peripheral T cells subsets: T-N, T-25, T-FN and T-R cells; T-25, T-FN and T-R cells after treatment with IL-2; and T-R cells transduced with empty, PDE3B-expressing or PDE3B(H801A)-expressing retroviral vectors
This data set is comprised of all peripheral (pooled lymph nodes and spleen) T cell subsets presented in this manuscript. These include T-N, T-25, T-FN and T-R cells; T-25, T-FN and T-R cells from mice treated with IL-2; and T-R cells transduced with empty, PDE3B-expressing or PDE3B(H801A)-expressi...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7280 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human thymic T cell subsets T-N, T-25, T-FN and T-R thymocytes
This data set is comprised of all thymic T cell subsets presented in this manuscript. These include T-N, T-25, T-FN and T-R thymocytes. Experiment Overall Design: Detailed methods are presented in the manuscript and in the attached Supplementary Information. All RNA samples were derived from cells i...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7770 | biostudies-arrayexpress
TranscriptomicsThe Transcriptionally Active Regions in the Genome of Bacillus subtilis
The majority of all genes have so far been identified and annotated systematically through in silico gene finding. Here we report the finding of 3,217 strand-specific Transcriptionally Active Regions (TARs) in the genome of Bacillus subtilis by the use of tiling arrays. We have measured the genome-...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2010-05-18 | E-GEOD-16086 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of ER71 EYFP positive/negative cells in ER71 WT and MT embryos
ER71 mutant embryos are nonviable and lack hematopoietic and endothelial lineages. To further define the functional role for ER71 in cell lineage decisions, we generated genetically modified mouse models. We engineered an ER71-EYFP transgenic mouse model by fusing the 3.9 kb ER71 promoter to the ...
ORGANISM(S): Mus musculus 
2011-11-02 | E-GEOD-32223 | biostudies-arrayexpress
MetabolomicsA large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS HILIC POS assay)
Perennial ryegrass (Lolium perenne) is integral to temperate pastoral agriculture, which contributes most of the milk and meat production worldwide. Chemical profiles and diversity of ryegrass offer several opportunities to harness specific traits and elucidate underlying biological mechanism...
2019-03-01 | MTBLS62 | MetaboLights
TranscriptomicsGene expression profiling in arterial tissue from type 2 diabetic patients
Gene expression profiling in arterial tissue from type 2 diabetic patients 10 patients with type 2 diabetes and 11 control subjects participated in the study
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-13760 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of inducible ES cells overexpressing Etv2 (induced for 12 hours at day 3 of differentiation)
During embryogenesis, the endothelial and the hematopoietic lineages first appear during gastrulation in the blood island of the yolk sac. We have previously reported that an Ets variant gene 2 (Etv2/ER71) mutant embryo lacks hematopoietic and endothelial lineages, however, the precise roles of Etv2...
ORGANISM(S): Mus musculus 
2012-07-03 | E-GEOD-37658 | biostudies-arrayexpress
TranscriptomicsB bifidum actively changes the gene expression profile induced by L acidophilus in murine dendritic cells
Dendritic cells (DC) play a pivotal regulatory role in activation of the innate as well as the adaptive part of the immune system by responding to environmental microorganisms. We have previously shown that some lactobacilli strains induce a strong production of the pro-inflammatory and Th1 polarizi...
ORGANISM(S): Mus musculus 
2010-02-24 | E-GEOD-20302 | biostudies-arrayexpress
TranscriptomicsLachancea kluyveri (formerly Saccharomyces kluyveri); Growth on different nitrogen sources.
Transcriptional profiling of the yeast Lachancea kluyveri when grown on minimal media with different compounds added as the sole nitrogen source. Cells grown on uracil, uridine, dihydrouracil and ammonia were profiled using cells grown on proline as the reference. Five conditions, of one was used as...
ORGANISM(S): Lachancea kluyveri 
2013-06-21 | E-GEOD-48135 | biostudies-arrayexpress
TranscriptomicsInsights into responses of human astrocytes to H5N1 infection by transcriptional analysis
Increasing evidence demonstrates influenza virus can not only affect the respiratory system, but also infect CNS and lead to CNS disorder and encephalopathy and encephalitis. Astrocytes are the most abundant cells in the CNS, which are capable of producing cytokines and neurotrophic factors and are ...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-66597 | biostudies-arrayexpress
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