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MetabolomicsUntargeted metabolomics profiling of esophageal tissues from a rat model of reflux esophagitis treated with Shunwei Jiangni Decoction

This dataset contains raw untargeted metabolomics data generated from esophageal tissue samples of rats in a reflux esophagitis (RE) model. The study aimed to characterize metabolic alterations associated with RE pathogenesis and to evaluate the regulatory effects of Shunwei Jiangni Decoction (SW...

2026-04-10 | MTBLS14112 | MetaboLights
MetabolomicsTissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have ...

2020-11-16 | MTBLS2052 | MetaboLights
MetabolomicsUntargeted gas chromatography–mass spectrometry-based metabolomics analysis of kidney and liver tissue from the Lewis Polycystic Kidney rat
Polycystic kidney disease (PKD) encompasses a spectrum of inherited disorders that lead to end-stage renal disease (ESRD). There is no cure for PKD and current treatment options are limited to renal replacement therapy and transplantation. A better understanding of the pathobiology of PKD is needed ...
2023-01-26 | MTBLS748 | MetaboLights
MetabolomicsMetabolite annotation of rat epididymis with High-resolution imaging mass spectrometry
Infertility or subfertility is a widespread problem with approximately 25% of couples seeking medical help. For about half the cases it lies in the male partner. Male infertility is caused by problems that affect sperm production, maturation and/or transport. In this study the role played by the epi...
2018-05-17 | MTBLS58 | MetaboLights
MetabolomicsTranscriptomic and lipidomic profiling of subcutaneous and visceral adipose tissues in 15 vertebrates
The storage of lipids as energy in adipose tissue (AT) has been conserved over the course of evolution. However, substantial differences in ATs physiological activities were reported between species. Hence, establishing the mechanisms shaping evolutionarily divergence in ATs transcriptomes could pro...
2022-11-17 | MTBLS5943 | MetaboLights
TranscriptomicsIdentification of sexually dimorphically expressed genes in rat tissues
The sexually dimorphic expression of genes across 26 somatic rat tissues was using Affymetrix RAE-230 genechips. We considered probesets to be sexually dimorphically expressed (SDE) if they were measurably expressed above background in at least one sex, there was at least a two-fold difference in ex...
ORGANISM(S): Rattus norvegicus 
2015-01-05 | E-GEOD-63362 | biostudies-arrayexpress
TranscriptomicsAn RNASeq normal tissue atlas for mouse and rat
The function of a gene is closely connected to its expression specificity across tissues and cell types. RNA-Seq is a powerful quantitative tool to explore genome wide expression. The aim of the present study is to provide a comprehensive RNA-Seq dataset across the same 13 tissues for mouse and rat,...
ORGANISM(S): Rattus norvegicus 
2017-10-25 | E-MTAB-6081 | biostudies-arrayexpress
TranscriptomicsProfile of small RNA transcriptome during cortical development in the Rat
Small non-coding RNAs play important roles in regulating gene expression during development and disease. However, a comprehensive analysis of small RNAs in developing brain is largely lacking. By using next-generation sequencing technique, we carried out a systematic analysis of small RNA transcript...
ORGANISM(S): Rattus norvegicus 
2012-06-25 | E-GEOD-27576 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat mammary tumors induced by N-methyl-N-nitrosurea (NMU) and normal mammary gland
Rat mammary tumors induced by N-methyl-N-nitrosurea (NMU) and normal mammary gland
ORGANISM(S): Rattus norvegicus 
2007-09-22 | E-GEOD-1872 | biostudies-arrayexpress
ProteomicsEffect of 3’,4’-dihydroxyflavonol eye drops in a rat model of dispase-induced proliferative vitreoretinopathy
Proliferative vitreoretinopathy (PVR) was induced in a rat model using intravitreal dispase to study fibrosis- and inflammation-related proteome changes and to evaluate the therapeutic effect of topical 3’,4’-dihydroxyflavonol (DiOHF) eye drops. Retina and vitreous were collected 28 days post-injury...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-01-05 | PXD068151 | Pride
Arpe-19 3’ 4’-dihydroxyflavonol Proliferative vitreoretinopathy  proteomics  rat mod-el of dispase-induced pvr. 
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