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ProteomicsLack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
Hypoxia Inducible Factor (HIF) prolyl hydroxylase domain (PHD) enzymes catalyse the posttranslational hydroxylation of conserved prolyl residues in the alpha-subunit of the HIF transcription factor. These modifications, which promote the degradation of HIF-alpha subunits by the pVHL E3 ligase comple...
ORGANISM(S): Homo sapiens (Human) 
2019-08-30 | PXD013112 | Pride
Human Lc-msms In vitro Phd enzyme Prolyl hydroxylation 
GenomicsHigh resolution genome-wide mapping of HIF binding sites by ChIP-seq
We report ChIP-Seq analysis of HIF-1 alpha, HIF-2 alpha, and HIF-1 beta binding in MCF-7 breast cancer cells Sample analysis compared to pre-immune serum chromatin immunoprecipitation
ORGANISM(S): Homo sapiens 
2011-04-05 | E-GEOD-28352 | biostudies-arrayexpress
TranscriptomicsThe role of HIF in FH-associated renal neoplasia
Fumarate hydratase (FH) mutations predispose to renal cysts cancer. These cancers overexpress hypoxia-inducible factor-alpha (Hif-1a). We have generated a conditional Fh1 (mouse FH) knockout mice that develop renal cysts and overexpress Hif-1a. In order to identify the contribution of Hif-1a to cyst...
ORGANISM(S): Mus musculus 
2011-10-23 | E-GEOD-29988 | biostudies-arrayexpress
GenomicsEGAD00000000060
Samples from the UK Glomerulonephritis DNA bank
EGAD00000000060 | EGA
GenomicsHLA has strongest association with IgA nephropathy in genome-wide analysis
GWAS study of families with probands with IgA nephropathy from the UK Glomerulonephritis DNA bank
EGAS00000000031 | EGA
GenomicsIgA Neuropathy Data Access Committee
Data Access Committee EGAC00000000013
EGAC00000000013 | EGA
UnknownBacille Calmette-Guerin vaccination to prevent febrile and respiratory illness in adults (BRACE): secondary outcomes of a randomised controlled phase 3 trial.
Not available
S-EPMC11106519 | biostudies-literature
UnknownBacillus Calmette-Guerin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial.
Not available
S-EPMC10500555 | biostudies-literature
UnknownRandomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers.
Not available
S-EPMC10497190 | biostudies-literature
UnknownHypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells.
Not available
S-EPMC8020087 | biostudies-literature
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