Sort   by:  
 Page size 
TranscriptomicsDepletion of the Cullin Cdc53p Induces Morphogenetic Changes in Candida albicans
Transcriptional profiling of CDC53 down-regulated Candida albicans cells compared to control cells Keywords: comparative genomic hybridization, genetic modification Candida albicans is an important opportunistic human fungal pathogen, which can cause mucosal as well as systemic infections in immun...
ORGANISM(S): Candida albicans 
2010-05-14 | E-GEOD-13976 | biostudies-arrayexpress
TranscriptomicsIdentification of the Candida albicans Cap1p regulon (Cap1-CSE-HA and Cap1-HA complete datasets)
Cap1p, a transcription factor of the basic region-leucine zipper family, regulates oxidative stress response (OSR) in Candida albicans. Alteration of its C-terminal cysteine-rich domain (CRD) results in Cap1p nuclear retention and transcriptional activation. To better understand the function of Ca...
ORGANISM(S): Candida albicans 
2010-05-18 | E-GEOD-15104 | biostudies-arrayexpress
TranscriptomicsIdentification of the Candida albicans CAP1 regulon
Cap1p, a transcription factor of the basic region-leucine zipper family, controls the oxidative stress response in Candida albicans. It was shown that alteration of the C-terminal cysteine-rich domain (CRD) of Cap1p results in nuclear retention and constitutive transcriptional activation. To further...
ORGANISM(S): Candida albicans 
2010-05-18 | E-GEOD-14258 | biostudies-arrayexpress
UnknownCancer-Related Cognitive Outcomes Among Older Breast Cancer Survivors in the Thinking and Living With Cancer Study.
Not available
S-EPMC7237199 | biostudies-literature
TranscriptomicsComparative xylose metabolism among the ascomycetes C. albicans, S. stipitis and S. cerevisiae
The ascomycetes Saccharomyces cerevisiae, Candida albicans and Scheffersomyces stipitis metabolize the pentose sugar xylose very differently. S. cerevisiae fails to grow on xylose, while C. albicans can grow, and S. stipitis can both grow and ferment xylose to ethanol. However, all three species co...
ORGANISM(S): Candida albicans SC5314 
2013-10-30 | E-GEOD-50476 | biostudies-arrayexpress
TranscriptomicsRegulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans
Constitutive overexpression of the Mdr1 efflux pump is an important mechanism of acquired drug resistance in the yeast Candida albicans. The zinc cluster transcription factor Mrr1 is a central regulator of MDR1 expression, but other transcription factors have also been implicated in MDR1 regulation....
ORGANISM(S): Candida albicans 
2011-07-01 | E-GEOD-23532 | biostudies-arrayexpress
TranscriptomicsPartial de-repression of the hyphal program does not restore hyphae formation in absence of a functional Arp2/3 complex
Deleting components of the Arp2/3 complex in Candida albicans resulted in a global lack of hyphal specific gene induction. This observation suggests that the failure in hyphal growth of Arp2/3 complex mutants could be a result of failure to activate hyphal specific genes. If the hyphal defect was pr...
ORGANISM(S): Candida albicans 
2010-01-22 | E-GEOD-19582 | biostudies-arrayexpress
TranscriptomicsArp2/3 complex mutants show a pronounced lack of hyphal specific gene expression in Candida albicans
Candida albicans is a diploid fungal pathogen lacking a defined complete sexual cycle, and thus has been refractory to standard forward genetic analysis. Instead, transcription profiling and reverse genetic strategies based on Saccharomyces cerevisiae have typically been used to link genes to functi...
ORGANISM(S): Candida albicans 
2010-10-08 | E-GEOD-19565 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression and location analyses of the Candida albicans Tac1p regulon
A major mechanism of azole resistance in Candida albicans is the over-expression of the genes encoding the ABC transporters Cdr1p and Cdr2p. Constitutive over-expression of these efflux pumps is due to mutations in the gene encoding Tac1p, resulting in hyperactivity of this zinc cluster transcripti...
ORGANISM(S): Candida albicans 
2010-05-25 | E-GEOD-8727 | biostudies-arrayexpress
TranscriptomicsForward genetics in Candida albicans reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis
This SuperSeries is composed of the following subset Series: GSE19565: Arp2/3 complex mutants show a pronounced lack of hyphal specific gene expression in Candida albicans GSE19582: Partial de-repression of the hyphal program does not restore hyphae formation in absence of a functional Arp2/3 comple...
ORGANISM(S): Candida albicans 
2010-05-15 | E-GEOD-19583 | biostudies-arrayexpress
Sort   by:  
 Page size