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Gene expression profile at single cell level of isogenic iPSC-derived primitive erythroblasts (RBCs), iPSC-derived definitive RBCs and Fetal liver-derived RBCs
Red blood cells (RBCs) from Plasmodium berghei ANKA infected mice were recovered to undergo 10X Chromium, droplet-based sequencing. Additionally, scRNAseq was performed on parasitised RBCs in the presence of systemic host inflammation induced by acute parasite infection or LPS conditioning. These an...
ORGANISM(S): Mus musculus 
We characterized the proteomic composition of RBCs from 53 breast cancer patients (stages I-III and IV), compared with 33 healthy donors. For that, we performed two different proteomic analyses (LC-MS/MS in DDA mode-shotgun- and a SWATH-MS) using the Triple TOF 6600 technology.
ORGANISM(S): Homo sapiens (Human) 
2023-01-17 | PXD030936 | Pride
The retention of a nucleus in the mature state of fish red blood cells (RBCs), and the ability to easily collect and manipulate blood in non-terminal experiments, makes it an ideal tissue on which to study the cellular stress response in fish. Through the use of the cGRASP 16K salmonid microarray, w...
ORGANISM(S): Oncorhynchus mykiss 

Circadian clocks coordinate mammalian behaviour and physiology enabling organisms to anticipate 24-hour cycles. Transcription-translation feedback loops are thought to drive these clocks in most of mammalian cells. However, red blood cells (RBCs), which do not contain a nucleus, and cannot perfor...

2020-11-13 | MTBLS1286 | MetaboLights
scRNAseq mapping asexual life-cycle progression of P.berghei ANKA parasitised RBCs in vivo with and without systemic host inflammation
We used a state of the art proteomics workflow, based upon nano-UPLC-MS\MS and advanced database searching to identify oxidative modifications to functional residues of hemoglobin subunit beta . Progressive accumulation of oxidized residues in stored erythrocytes and selective removal in vesicles wa...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-04 | MSV000080222 | MassIVE
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