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UnknownCorrelation between restriction endonuclease analysis and PCR ribotyping for the identification of Clostridioides (Clostridium) difficile clinical strains.
Not available
S-EPMC6924008 | biostudies-literature
UnknownEpidemiology of Clostridioides difficile infection at one hospital 10 years after an outbreak of the epidemic C. difficile strain BI/027: changing strain prevalence, antimicrobial susceptibilities, and patient antibiotic exposures.
Not available
S-EPMC11304679 | biostudies-literature
UnknownComparative genomics analysis of Clostridium difficile epidemic strain DH/NAP11/106.
Not available
S-EPMC5911408 | biostudies-literature
TranscriptomicsAn epithelial-mesenchymal transition (EMT) gene signature predicts resistance to erlotinib and PI3K pathway inhibitors and identifies Axl as a novel EMT marker in non-small cell lung cancer.
Epithelial/mesenchymal transition (EMT) is associated with loss of cell adhesion molecules, such as E-cadherin, and increased invasion, migration, and proliferation in epithelial cancers. In non-small cell lung cancer (NSCLC), EMT is associated with greater resistance to EGFR inhibitors. However, it...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-33072 | biostudies-arrayexpress
GenomicsICOS-mediated inactivation of the FOXO1 transcription factor in the differentiation of T follicular helper cells
T follicular helper (Tfh) cells constitute an essential cell type in the induction of antibodies. We report that CD4 T cells lacking Foxo1 almost uniformly became CXCR5int Tfh cells following immunization. Moreover, a Foxo1 loss-of-function complemented an Icos mutation allowing the appearance of Tf...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-46525 | biostudies-arrayexpress
TranscriptomicsExpression data from TKI258 treated 4T1 cells
4T1 mouse mammary carcinoma cells have an autocrine FGFR active loop leading to constitutive activation of downstream signaling pathways. We found that FGFR inhibitors have a strong effect on the proliferation and survival of these cells. We used microarray to understand the contribution of FGFR sig...
ORGANISM(S): Mus musculus 
2010-07-07 | E-GEOD-19220 | biostudies-arrayexpress
TranscriptomicsExpression data from TKI258 treated 4T1 tumors
4T1 mouse mammary carcinoma cells have an autocrine FGFR active loop leading to constitutive activation of downstream signaling pathways. We found that FGFR inhibitors have a strong effect on 4T1 tumors in-vivo. We used microarray to understand the contribution of FGFR signaling to the tumor formati...
ORGANISM(S): Mus musculus 
2010-07-07 | E-GEOD-19221 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human brain samples from HIV infected individuals with HIV encephalitis vs controls
The neurodegenerative process in HIV encephalitis (HIVE) is associated with extensive damage to the dendritic and synaptic structure that often leads to cognitive impairment. Several mechanisms might be at play, including release of neurotoxins, oxidative stress and decreased activity of neurotrophi...
ORGANISM(S): Homo sapiens 
2007-12-14 | E-GEOD-3489 | biostudies-arrayexpress
UnknownClinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients.
Not available
S-EPMC6533620 | biostudies-literature
TranscriptomicsTranscription profiling of mouse D10.G4.1 T-cells treated with neuromedin U for different length of time to study the effect of neuromedin on gene expression in T cells.
Effects of Neuromedin-U on gene expression in mouse D10.G4.1 T-cells natively expressing the GPCR Axor13
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-1791 | biostudies-arrayexpress
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