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ProteomicsRecapitulating the Human Myotendinous Junction In Vitro Using a 3D Bioprinted Model
The myotendinous junction (MTJ) is a critical interface connecting skeletal muscle and tendon, responsible for transmitting contractile forces and ultimately enabling musculoskeletal movement. Due to its complex architecture, the MTJ is particularly susceptible to injury under conditions of excessiv...
ORGANISM(S): Homo sapiens (Human) 
2026-01-30 | PXD072245 | Pride
ProteomicsDevelopment of a 3D fatty infiltration platform to model, at higher scale, the impact of LY2090314 compound on fibro/adipogenic progenitor adipogenic drift
In human dystrophies, the progressive muscle wasting is exacerbated by ectopic deposition of fat and fibrous tissue originating from fibro/adipogenic progenitors (FAPs). In degenerating muscles, the ability of these cells to adjuvate a successful healing is attenuated and FAPs aberrantly expand and ...
ORGANISM(S): Homo sapiens (Human) 
2023-06-13 | PXD040479 | Pride
Ly2090314 Faps Duchenne muscular dystrophy Adipogenesis B-catenin 
UnknownPBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain.
Not available
S-EPMC140055 | biostudies-literature
Proteomics3D bioprinting directly affects proteomic signature and myogenic maturation in muscle pericytes-derived human myo-substitute
Skeletal muscle tissue engineering (SMTE) has recently emerged to address major clinical challenges such as volumetric muscle loss. Here, we report a rotary wet-spinning (RoWS) biofabrication technique for producing human myo-substitutes with biomimetic architectures and functions. Here, we demonstr...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD043605 | Pride
Myogenic maturation Myosubstitute Bioprinting Perycites 
TranscriptomicsRNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice
We purified FAPs from the hind limbs of wild type, mdx and cardiotoxin-injured mice in order to unveil changes in their transcriptomes. RNA was isolated directly from sorted cells and analyzed by 3’ RNA sequencing.
ORGANISM(S): Mus musculus 
2019-06-20 | E-MTAB-8040 | biostudies-arrayexpress
UnknownThe intellectual disability protein RAB39B selectively regulates GluA2 trafficking to determine synaptic AMPAR composition.
Not available
S-EPMC4383008 | biostudies-literature
UnknownRisk of clinical events in virologically suppressed people with HIV switching to a two-drug regimen vs. remaining on a three-drug regimen: a target trial emulation.
Not available
S-EPMC12309018 | biostudies-literature
UnknownRole of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy and Collagen quality control
Not available
S-SCDT-EMBOR-2020-52289-T | biostudies-other
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