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ProteomicsIdentify Yeast Proteasome Cross-links with Multiple Ion Fragmentation Methods
Use of EThcD, CID, HCD and high energy HCD to identify protein cross-links
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-06-18 | PXD018310 | Pride
Yeast Proteasome Cross-links 
ProteomicsStructural Analysis of a Prokaryotic Ribosome Using a Novel Amidinating Cross-Linker and Mass Spectrometry
The structure of the Escherichia coli ribosome, a 2.5 MDa ribonucleoprotein complex containing more than 50 proteins, was probed using the novel amidinating cross-linker diethyl suberthioimidate (DEST) and mass spectrometry. Peptide cross-links derived from this complex structure were identified at ...
ORGANISM(S): Escherichia coli 
2015-12-23 | PXD003381 | Pride
Amidination Dest E. coli Mass spectrometry Diethyl suberthioimidate Ribosome Protein cross-linking 
MetabolomicsAcute heat stress amplifies exercise-induced metabolomic perturbations and reveals variation in circulating amino acids in endurance-trained males

Using untargeted metabolomics, we aimed to characterise the systemic impact of environmental heat stress during exercise. Twenty-three trained male triathletes completed a 30-min exercise test in hot (35°C) and temperate (21°C) conditions. Venous blood samples were collected immediately pre- and ...

2025-08-14 | MTBLS6051 | MetaboLights
TranscriptomicsThe genomic landscape of cohesin-associated chromatin interactions
Cohesin is implicated in establishing tissue-specific DNA loops that target enhancers to promoters, and also localizes to sites bound by the insulator protein CTCF, which blocks enhancer-promoter communication. However, cohesin-associated interactions have not been characterized on a genome-wide sca...
ORGANISM(S): Mus musculus 
2013-05-22 | E-GEOD-42237 | biostudies-arrayexpress
TranscriptomicsChromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb.
The regulatory elements that direct tissue-specific gene expression in the developing mammalian embryo remain largely unknown. Although chromatin profiling has proven to be a powerful method for mapping regulatory sequences in cultured cells, chromatin states characteristic of active developmental e...
ORGANISM(S): Mus musculus 
2012-03-16 | E-GEOD-30641 | biostudies-arrayexpress
MetabolomicsGNPS - Bacterial Bile Acid Amidates (BBAAs) data set
Data acquired for conjugated bile acids with amino acids analysis of human fecal samples by targeted LC-MS. These samples are a part of a study investigating a new BSH function as an amine N-acyl transferase that conjugates amines to form bacterial bile acid amidates (BBAAs).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-18 | MSV000093144 | GNPS
UnknownMeta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years.
Not available
S-EPMC5299468 | biostudies-literature
UnknownEfficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico.
Not available
S-EPMC8693692 | biostudies-literature
UnknownEffects of combination lipid therapy in type 2 diabetes mellitus.
Not available
S-EPMC2879499 | biostudies-literature
UnknownEffect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial.
Not available
S-EPMC4123233 | biostudies-literature
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