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TranscriptomicsRelA and RelB-dependent transcriptome analysis in lymphotoxin-ß receptor stimulated mouse embryonic fibroblasts
Background: Lymphotoxin signaling via the lymphotoxin-β receptor (LTβR) has been implicated in several biological processes, ranging from development of secondary lymphoid organs, maintenance of splenic tissue, host defense against pathogens, autoimmunity, and lipid homeostasis. The major transcript...
ORGANISM(S): Mus musculus 
2008-12-17 | E-GEOD-11963 | biostudies-arrayexpress
ProteomicsThe Escherichia coli RelB antitoxin C-terminus is essential for RelE toxin suppression and transcriptional repression.
Bacterial type II toxin-antitoxin (TA) systems exhibit high specificity within each pair to ensure precise recognition of the toxin by its cognate antitoxin to inhibit toxicity of the free toxin. Despite high structural similarity among some TAs, crosstalk between noncognate TA pairs is rare. To det...
ORGANISM(S): Escherichia coli 
2025-07-06 | PXD065338 | Pride
Relb E coli Antitoxin 
ProteomicsRelB function in lipid metabolism
Study of the role of the transcription factor RelB (alternative NF-kappaB subunit) in the control of lipid metabolism.
ORGANISM(S): Homo sapiens (Human) 
2026-09-28 | PXD074627 | Pride
Hcc derived cell lines 
GenomicsGenome-wide analysis of Wild Type and Relb-/- MEFs
Genome-wide analysis of Wild Type and Relb-/- MEFs
PRJNA736594 | ENA
TranscriptomicsComparison of RelB-/- and RelB+/- thymi
Thymic medullary epithelial cell (mTEC) expression of the autoimmune regulator AIRE, and of tissue-specific antigens, is controlled by members of the non-canonical NF-kB signalling pathway, including RelB and NF-kB2. Of the genes in this pathway, RelB-/- mice develop a particularly severe multi-orga...
ORGANISM(S): Mus musculus 
2012-12-27 | E-GEOD-43154 | biostudies-arrayexpress
ModelsNIK-dependent p100 processing into p52 with RelB binding and IkBd degradation, mass action, SBML 2v4
This model represents NIK-dependent p100 processing into p52 followed by binding to RelB and NIK-dependent IkBd degradation. This model assesses the impact of substrate complex competition on RelB-p52.
2024-09-02 | BIOMD0000000871 | BioModels
TranscriptomicsThe chromatin protein Nupr1 regulates RelB-dependent NF-kB events necessary for pancreatic cancer development
The objective of this study was to elucidate the role of Nupr1 in pancreatic tumorigenesis. Using the Pdx-1-cre;LSL-KrasG12D mouse as model we discovered that, in contrast to KrasG12D pancreas that develop multiple foci of pancreatic intraepithelial neoplasia (PanIN), KrasG12D;Nupr1KO pancreas were ...
ORGANISM(S): Homo sapiens 
2012-02-01 | E-GEOD-35463 | biostudies-arrayexpress
GenomicsTranscriptomic analysis of Tregs from RelB-dDC mice
Transcriptomic analysis of Tregs from RelB-dDC mice
PRJNA556427 | ENA
TranscriptomicsComparison of RelB-/- and RelB+/- thymi
Thymic medullary epithelial cell (mTEC) expression of the autoimmune regulator AIRE, and of tissue-specific antigens, is controlled by members of the non-canonical NF-kB signalling pathway, including RelB and NF-kB2. Of the genes in this pathway, RelB-/- mice develop a particularly severe multi-orga...
ORGANISM(S): Mus musculus 
2012-12-27 | GSE43154 | GEO
GenomicsRole of RelB in Interferon Dependent and Indpendent Gene Regulation
Role of RelB in Interferon Dependent and Indpendent Gene Regulation
PRJNA931364 | ENA
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