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GenomicsDNA Cytosine Hydroxymethylation Levels Are Distinct Among Peripheral Blood Leukocytes
Peripheral blood leukocytes are the most commonly used surrogates to study epigenome-induced risk and epigenomic response to disease related stress. We considered the hypothesis that the TET enzyme catalyzed hydroxymethylation of 5mC to 5hmC might vary among peripheral blood leukocytes and reflect t...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-70519 | biostudies-arrayexpress
UnknownXUV fluorescence as a probe of interatomic coulombic decay of resonantly excited He nanodroplets.
Not available
S-EPMC12796158 | biostudies-literature
MetabolomicsExercise Activates Interferon Immune Response of the Liver via Gpld1 to Enhance Antiviral Innate Immunity

Healthy behavioral patterns could modulate organ functions to enhance the body’s immunity. However, whether exercise regulates antiviral innate immunity remains elusive. Here, we found that exercise promotes type-I IFN (IFN-I) production in the liver and enhances IFN-I immune activity of the body...

2024-04-24 | MTBLS7972 | MetaboLights
ProteomicsAnalysis of muscular proteomics of deep pressure ulcers reveals JAK2 influence on muscle autophagy and apoptosis
Pressure ulcers (PU) is a complex and serious clinical problem. Deep tissue injury is either the outcome or the trigger of deep PU. However, the cellular and molecular mechanisms that contribute to the pathogenesis of deep PU remain unclear. In this study, the degeneration characteristics, increased...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD009512 | Pride
Proteomics Ischemia/reperfusion injury Deep pressure ulcers Jak2 Autophagy & apoptosis 
MetabolomicsBased on the Metabolomic Approach the Energy Metabolism Responses of Oriental River Prawn Macrobrachium nipponense Hepatopancreas to Acute Hypoxia and Reoxygenation
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
UnknownDysregulated lipid metabolism in kidney stone pathogenesis: a literature review of mechanistic insights and therapeutic implications.
Not available
S-EPMC12362858 | biostudies-literature
TranscriptomicsExpression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein.
Local renin antiotensin systems have been identified for many extra-renal sites. Bone marrow has been proposed as one such site, although the nature of the renin-expressing cell type(s) has not been established. Affymetrix microarrays were used to characterize the expression profile of renin-express...
ORGANISM(S): Mus musculus 
2014-02-17 | E-GEOD-53916 | biostudies-arrayexpress
ProteomicsTargeted plasma proteomics reveals organ damage signatures of AIDS-related and non-communicable chronic diseases-related deaths in HIV population
This project investigates the role of protein biomarkers in differentiating the underlying causes of mortality among people with HIV (PWH). With antiretroviral therapy (ART) significantly reducing deaths from opportunistic infections, noncommunicable chronic diseases (NCDs) have emerged as a leading...
ORGANISM(S): Homo sapiens (Human) 
2025-04-15 | PAD000008 | Pride
Human Hiv Olink 
Proteomicspig liver proteomics of N-glycosylation modification
This research investigated the proteomics of total proteins and N-glycosylation modification from groups between Wuzhishan and Large White pigs at 4-month-old, and Wuzhishan pigs at 4-month-old and 8-month-old.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-03-16 | PXD056683 | Pride
Pigs Proteomics Liver N-glycosylation 
UnknownThe Role of Cell Division Autoantigen 1 (CDA1) in Renal Fibrosis of Diabetic Nephropathy.
Not available
S-EPMC8102118 | biostudies-literature
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