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X chromosome inactivation (XCI) is a dosage compensation mechanism in female cells to regulate X-linked gene expression. We report here that subcultures from established lines of female hESCs displayed variations (0-100%) in the expression of XCI markers such as XIST RNA coating and enrichment of h...
ORGANISM(S): Homo sapiens 
X-Adrenoleukodystrophy (X-Ald) disease progression was studied by comparing expression patterns of Abcd1 -/- mouse spinal cords from 3.5, 12 and 22 months of age compared to healthy littermates spinal cords at the same time points.
ORGANISM(S): Mus musculus 
In C. elegans, a condensin-like protein complex associates specifically with both X chromosomes of XX animals to execute dosage compensation. Dosage Compensation Complex (DCC) reduces the level of transcripts arising from each of the two X chromosomes. Recruitment to X is specified in part by discre...
ORGANISM(S): Caenorhabditis elegans 
miRNA profile analysis of two mesothelioma cell lines (MPP89 and REN), and of HMC-TERT non tumoral mesothelial cells
ORGANISM(S): Homo sapiens 
modENCODE_submission_695 This submission comes from a modENCODE project of Jason Lieb. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The focus of our analysis will be elements that specify nucleosome positioning and occupancy, control domains of gene expressio...
ORGANISM(S): Caenorhabditis elegans 
modENCODE_submission_696 This submission comes from a modENCODE project of Jason Lieb. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The focus of our analysis will be elements that specify nucleosome positioning and occupancy, control domains of gene expressio...
ORGANISM(S): Caenorhabditis elegans 
modENCODE_submission_701 This submission comes from a modENCODE project of Jason Lieb. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The focus of our analysis will be elements that specify nucleosome positioning and occupancy, control domains of gene expressio...
ORGANISM(S): Caenorhabditis elegans 
Biological tissues are exposed to X-rays under controlled conditions in both medical applications (diagnostic imaging and radiotherapy) and research studies (e.g. microcomputed X-ray tomography: microCT). Radiotherapy regimes may deliver doses of up to 50Gy to both the target tumour and to healthy t...
ORGANISM(S): Gallus gallus (Chicken) 
2025-03-11 | PXD050691 | Pride
Biological tissues are exposed to X-rays under controlled conditions in both medical applications (diagnostic imaging and radiotherapy) and research studies (e.g. microcomputed X-ray tomography: microCT). Radiotherapy regimes may deliver doses of up to 50Gy to both the target tumour and to healthy t...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-03-11 | PXD050686 | Pride
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