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TranscriptomicsCcpA, a Pleiotropic Key Regulator in Butanol-producing Clostridium acetobutylicum ATCC 824
Clostridium acetobutylicum is a typical bacterium of major importance to industrial butanol production. In order to dissect the regulatory network pertaining to the industrial application of this bacterium, catabolite control protein A (CcpA) was investigated for its global function by DNA microarra...
ORGANISM(S): Clostridium acetobutylicum 
2012-08-30 | E-GEOD-33364 | biostudies-arrayexpress
UnknownGenome-wide identification and characterization of the NF-Y gene family in grape (vitis vinifera L.).
Not available
S-EPMC4982312 | biostudies-literature
TranscriptomicsDifferential effects of TNFalpha and IL1beta on FLS global gene expression profile
TNFalpha and IL1beta play a pathogenic role in rheumatoid arthritis. Both cytokines are known to activate cytokine and metalloproteinase secretion by synovial fibroblasts. In the present study, we wanted to investigate whether TNFalpha and IL1beta displayed differential effects on cultured Fibroblas...
ORGANISM(S): Homo sapiens 
2009-04-15 | E-GEOD-15615 | biostudies-arrayexpress
TranscriptomicsDynamic remodeling of histone modifications in response to osmotic stress in Saccharomyces cerevisiae
Specific histone modifications play important roles in chromatin functions such as activation or repression of gene transcription. These participation must occur as a dynamic process, however, most of histone modification state maps reported to date only provide static pictures linking certain modif...
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-06 | E-GEOD-41587 | biostudies-arrayexpress
TranscriptomicsThe activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65 II
The inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate transcriptional programs in the genome. We determined the genome-wide binding of the TAK1-controlled NF-M-NM-:B subunit p65 in relation to active enhancers a...
ORGANISM(S): Homo sapiens 
2014-12-17 | E-GEOD-64237 | biostudies-arrayexpress
Transcriptomicsm6A-dependent regulation of messenger RNA stability
N6-methyladenosine (m6A) is the most prevalent internal modification present in the mRNA of all higher eukaryotes. Here we present that m6A is selectively recognized by human YTH domain family (YTHDF2) protein to regulate mRNA degradation. By using crosslinking and immunoprecipitation, we have ident...
ORGANISM(S): Homo sapiens 
2013-11-29 | E-GEOD-49339 | biostudies-arrayexpress
TranscriptomicsChIP-chip of Spo14 and Mvp1
Genome-wide localization of two new RNA pol II interacting proteins. We use C-LYTAG to map binding sites of Spo14 and Mvp1 along the S. cerevisiae genome. Two biological replicates of each experiment were done. Keywords: ChIp-chip Two independent biological replicates of each IP. We used three macr...
ORGANISM(S): Saccharomyces cerevisiae 
2011-10-31 | E-GEOD-16905 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression in mLTC-1 cells following siRNA-mediated Gata4 inhibition
The effects of Gata4 inhibition on global gene expression in mLTC-1 cells was analysed. Using microarray analysis we identified a set of genes that are downregulated or upregulated following siRNA-mediated silencing of Gata4 in the murine Leydig tumor cell line mLTC-1. Among the downregulated genes...
ORGANISM(S): Mus musculus 
2015-02-23 | E-GEOD-63320 | biostudies-arrayexpress
TranscriptomicsThe activation of IL-1 induced enhancers depends on TAK1 kinase activity and NF-KB p65
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-12-16 | E-GEOD-64224 | biostudies-arrayexpress
TranscriptomicsTranscripts regulated by elevated DKF-2 (WT background)
Transcriptional profiling was used to determine why DKF-2 (protein kinase D) deficiency and surfeit caused hypersensitivity and resistance, respectively, to a bacterial pathogen (P. aeruginosa 14). The studies show that DKF-2 contributes to C. elegans innate immunity by inducing expression of >75 ge...
ORGANISM(S): Caenorhabditis elegans 
2009-01-12 | E-GEOD-12456 | biostudies-arrayexpress
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