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ProteomicsLysine methylation promotes NFAT5 activation upon EGFR activation and predicts response to temozolomide
Temozolomide (TMZ) therapy offers minimal clinical benefits in patients with glioblastoma multiforme (GBM) with high EGFR activity, underscoring the need for effective combination therapy. Here, we show that tonicity-responsive enhancer binding protein (NFAT5) lysine methylation, is a determinant of...
ORGANISM(S): Homo Sapiens 
2022-11-01 | PXD037869 |
ProteomicsPhosphorylation regulation of cardiac proteins in Babesia microti infected mice in an effort to restore heart function
The dynamic changes of all proteins in the heart of mice infected with Babesia were studied by using DIA quantitative proteomics technology, and the regulation strategy of proteins in the heart of mice infected with Babesia was discussed.
ORGANISM(S): Mus Musculus 
2021-11-01 | PXD029452 |
ProteomicsThe quantitative and phosphorylation proteomics analysis of mouse liver after tick-borne Babesia microti infection
Babesia microti is a tick-borne protozoan parasite that infects the red blood cells of mice, humans, and other mammals. Hosts infected with B. microti exhibit a series of clinical symptoms, including fever, anaemia, and haemoglobinuria, and multiple-organ injury. The infection can even result in dea...
ORGANISM(S): Mus Musculus 
2020-03-19 | PXD018102 |
ProteomicsPhosphorylated protein data of proteomics of spleen infected by Babesia microti
Babesia is a kind of protozoa parasitic in the red blood cells of some vertebrates. Some species of Babesia can cause human and animal co-infection and do great harm. As the largest immune organ in mammals, spleen plays an important role in resisting Babesia infection. Although the spleen infected b...
ORGANISM(S): Babesia Microti 
2020-05-21 | PXD019319 |
ProteomicsGlobal protein data of proteomics of spleen infected by Babesia microti
Babesia is a kind of protozoa parasitic in the red blood cells of some vertebrates. Some species of Babesia can cause human and animal co-infection and do great harm. As the largest immune organ in mammals, spleen plays an important role in resisting Babesia infection. Although the spleen infected b...
ORGANISM(S): Babesia Microti 
2020-05-16 | PXD019236 |
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