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The transcriptome of the planarian Schmidtea mediterranea is not well characterized. We have used RNA-Seq to characterize the transcriptome in both sexual and asexual strains of S. mediterranea from both untreated and irradiated animals. Moreover, we have performed RNA-Seq on RNA purified from FAC...
ORGANISM(S): Schmidtea mediterranea 
Our study aims to compare 2D adherent and 3D floating (spheroid) cell cultures of in the context of cellular physiology and in atherosclerosis modelling. Here, we utilize vascular smooth muscle cells from rat aorta to profile 2D and 3D proteomes.
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-07 | PXD069144 | Pride
AID promotes chromosomal translocations by inducing DNA double-strand breaks (DSBs) at immunoglobulin (Ig) genes and oncogenes in G1. RPA is a ssDNA-binding protein that associates with resected DSBs in the S phase and facilitates the assembly of factors involved in homologous repair (HR) such as R...
ORGANISM(S): Mus musculus 
Caspase-4 and caspase-5 have been linked to the sensing of Gram-negative bacteria and their extracellular vesicles (EVs). Recent studies suggested that Gram-positive bacteria can be sensed through signaling cascades involving these two caspases. In the present study, we report that S. pyogenes secre...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD046570 | Pride
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