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MetabolomicsHyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells
Premature infants require oxygen supplementation to survive, but excess oxygen causes retinovascular growth suppression that underlies the leading cause of infant blindness known as retinopathy of prematurity (ROP). We analyzed changes in intermediary metabolism during hyperoxia in human retinal end...
2020-03-12 | MTBLS1228 | MetaboLights
MetabolomicsRat Retinal Detachment Metabolomics Timecourse
Not available
ORGANISM(S): Rattus norvegicus 
ST000832 | MetabolomicsWorkbench
MetabolomicsRetinal ganglion cells lipid profiling
Not available
ORGANISM(S): Mus musculus 
ST001105 | MetabolomicsWorkbench
ProteomicsRetinal-cysteine adduct in Opn5L1
Targeted analysis of retinal-cysteine adduct in Opsin 5 like-1 (Opn5L1) protein Chicken Opn5L1 E177K/Q192K mutant was expressed in HEK293T, regenerated by all-trans-retinal, solubilized by dodecyl maltoside, and purified using Rho1D4 antibody-conjugated Sephalose. Semi-quantitative targeted analyses...
ORGANISM(S): Gallus Gallus 
2018-02-15 | PXD008890 | JPOST Repository
TranscriptomicsTranscriptomic analysis of human retinal detachment (RD) reveals both inflammation and photoreceptor death
We have used surgical specimens to perform a differential analysis of the transcriptome of human retinal tissues following detachment. Data analysis reveals major involvement of the immune response in the disease and interindividual variation was monitored to unravel a second crucial aspect of the p...
ORGANISM(S): Homo sapiens 
2012-03-06 | E-GEOD-28133 | biostudies-arrayexpress
ProteomicsRetinal proteomic profiling in the course of experimental glaucoma
Intraocular pressure was elevated through episkleral vein occlusion by thermic cauterization of SD rats. Animals were further sacrificed after different periods of elevated IOP and the retinal proteins were investigated for alterations regarding the relative protein level in this experimental model ...
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2017-11-28 | MSV000081757 | MassIVE
TranscriptomicsRNA-seq of retinal organoids differentiated from hESCs carrying mutations in the RB1 gene
hESC lines carrying deleterious mutations in the RB1 gene in heterozygous and homozygous state were generated by genome-editing based on CRISPR/Cas9. Parental cell line and genome-edited cell lines were differentiated into retinal organoids for 152 days based on the Protocol published by Döpper et a...
ORGANISM(S): Homo sapiens 
2022-05-10 | E-MTAB-10331 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of zebrafish embryonic retinal pigment epithelium in vivo
Eye development and photoreceptor maintenance requires the retinal pigment epithelium (RPE), a thin layer of cells that underlies the neural retina. Despite its importance, RPE development has not been studied by a genomic approach. A microarray expression profiling methodology was established in th...
ORGANISM(S): Danio rerio 
2008-06-13 | E-GEOD-5048 | biostudies-arrayexpress
ProteomicsBasement Membranes from Human Retinal Blood Vessels, Inner Limiting Membranes, and Lens Capsules
Three types of BMs from adult human eyes, the inner limiting membrane, the retinal vascular BMs and the lens capsule, were isolated for analysis by 1D-SDS-PAGE and LC-MS/MS.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081772 | MassIVE
TranscriptomicsExpression profiling of the retinal pigment epithelium in zebrafish smarca4 mutant
Purpose: The purpose of this study was to develop a framework for analyzing RPE expression profiles from zebrafish eye mutants. Methods: The fish model we used was smarca4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4), a retinal dystrophic muta...
ORGANISM(S): Danio rerio 
2014-01-03 | E-GEOD-50241 | biostudies-arrayexpress
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