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TranscriptomicsRNAi triggered by specialized machinery silences developmental genes and retrotransposons (ChIP-chip)
RNAi is a conserved mechanism in which small interfering RNAs (siRNAs) guide the degradation of cognate RNAs, but also promote heterochromatin assembly at repetitive DNA elements such as centromeric repeats. However, the full extent of RNAi functions and its endogenous targets have not been explored...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-26 | E-GEOD-41642 | biostudies-arrayexpress
TranscriptomicsRNAi triggered by specialized machinery silences developmental genes and retrotransposons (RNA-Seq)
RNAi is a conserved mechanism in which small interfering RNAs (siRNAs) guide the degradation of cognate RNAs, but also promote heterochromatin assembly at repetitive DNA elements such as centromeric repeats. However, the full extent of RNAi functions and its endogenous targets have not been explored...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-26 | E-GEOD-41634 | biostudies-arrayexpress
GenomicsDirect cell-to-cell transmission of retrotransposons
Direct cell-to-cell transmission of retrotransposons
PRJNA1236372 | ENA
TranscriptomicsSuv39h-dependent H3K9me3 represses intact retrotransposons in mouse embryonic stem cells
Heterochromatin is required to restrict aberrant expression of retrotransposons, but it remains poorly defined due to the underlying repeat-rich sequences. We dissected Suv39h-dependent histone H3 lysine 9 trimethylation (H3K9me3) by genome-wide ChIP-sequencing in mouse embryonic stem cells (ESCs). ...
ORGANISM(S): Mus musculus 
2014-06-26 | E-GEOD-57092 | biostudies-arrayexpress
GenomicsTemporal Lobe Epilepsy and Retrotransposons
Temporal Lobe Epilepsy and Retrotransposons
PRJNA647483 | ENA
GenomicsTemporal Lobe Epilepsy and Retrotransposons
Temporal Lobe Epilepsy and Retrotransposons
PRJNA647484 | ENA
ProteomicsDirect cell-to-cell transmission of retrotransposons
Transposable elements are abundant in host genomes but are generally considered to be confined to the cell in which they are expressed, with the notable exception of endogenous retroviruses. Here, we identify a group of LTR retrotransposons that infect the germline from somatic cells within the Dros...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-03-21 | PXD061763 | Pride
Endogenous retroviruses Infectivity Drosophila Transposable elements Ovaries 
GenomicsDirect cell-to-cell transmission of retrotransposons [Minion]
Direct cell-to-cell transmission of retrotransposons [Minion]
PRJNA1236369 | ENA
GenomicsDirect cell-to-cell transmission of retrotransposons [RNA-seq]
Direct cell-to-cell transmission of retrotransposons [RNA-seq]
PRJNA1236371 | ENA
GenomicsGenome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria
During transcription the nascent RNA can invade the DNA template, forming extended RNA-DNA duplexes (R-loops). Here we employ ChIP-seq in strains expressing or lacking RNase H to map targets of RNase H activity throughout budding yeast genome. In wild-type strains, R-loops were readily detected over...
ORGANISM(S): Saccharomyces cerevisiae 
2014-11-03 | E-GEOD-53420 | biostudies-arrayexpress
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