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ProteomicsMoonlighting chaperone 1 activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa
Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three intertwined quorum sensing systems control virulence of P. aeruginosa, with the rhl circuit playing the leading role in late and ...
ORGANISM(S): Pseudomonas aeruginosa PA14 
2023-03-11 | PXD038000 | Pride
Rhlr Pseudomonas aeruginosa Pqse Quorum sensing Lc-ms/ms 
GenomicsPseudomonas aeruginosa RhlR ChIP-seq
Pseudomonas aeruginosa RhlR ChIP-seq
PRJEB62488 | ENA
GenomicsRNA-seq for MvfR, RhlR and QscR
RNA-seq for MvfR, RhlR and QscR
PRJNA496467 | ENA
GenomicsPseudomonas aeruginosa RhlR ChIP-seq
We performed ChIP-seq analyses of RhlR to map the C4-homoserine lactone-dependent and PqsE-dependent RhlR binding sites in the P. aeruginosa genome.
ORGANISM(S): Pseudomonas aeruginosa 
2023-06-10 | E-MTAB-12966 | biostudies-arrayexpress
TranscriptomicsExpression profile for PA14 lasR rhlR double mutant with H2O2 stress
Quorum sensing controls the expression of multiple virulence factors. PA14 genes lasR and rhlR are necessary for quorum sensing via homoserine lactones. A PA14 lasR rhlR deficient mutant exhibits a reduced oxidative stress response. Here we conducted a microarray to determine oxidative stress resp...
ORGANISM(S): Pseudomonas aeruginosa 
2015-01-09 | E-GEOD-54245 | biostudies-arrayexpress
GenomicsPqsE expands and differentially modulates the RhlR quorum sensing regulon in Pseudomonas aeruginosa
PqsE expands and differentially modulates the RhlR quorum sensing regulon in Pseudomonas aeruginosa
PRJNA826892 | ENA
TranscriptomicsRNA-seq for MvfR, RhlR and QscR
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen of humans, most notably those with cystic fibrosis or whose immune systems are compromised. As a global regulator, MvfR,RhlR and QscR have been characterized to control a group of virulence-related factors and quorum sensing (QS) genes...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2019-07-16 | GSE121243 | GEO
UnknownThe PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in Pseudomonas aeruginosa.
Not available
S-EPMC8754118 | biostudies-literature
TranscriptomicsPqsE expands and differentially modulates the RhlR quorum sensing regulon in Pseudomonas aeruginosa
While it is known that PqsE can stimulate the ability of RhlR to control some virulence factors, no data are available allowing clear discrimination of the PqsE and RhlR regulons. In this study, a P. aeruginosa PAO1 mutant strain with deletion of multiple QS elements and inducible expression of PqsE...
ORGANISM(S): Pseudomonas aeruginosa 
2022-05-17 | GSE200835 | GEO
TranscriptomicsExpression profile for PA14 lasR rhlR double mutant with H2O2 stress
Quorum sensing controls the expression of multiple virulence factors. PA14 genes lasR and rhlR are necessary for quorum sensing via homoserine lactones. A PA14 lasR rhlR deficient mutant exhibits a reduced oxidative stress response. Here we conducted a microarray to determine oxidative stress respon...
ORGANISM(S): Pseudomonas aeruginosa 
2015-01-09 | GSE54245 | GEO
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