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ProteomicsThe PqsE Protein Interaction Network in Pseudomonas aeruginosa
The PqsE enzyme plays a vital role in quorum sensing and virulence in Pseudomonas aeruginosa, yet its enzymatic function is unknown. Here, we identify the protein interaction network of PqsE as well as that of a catalytically dead variant, PqsE(D73A) in P. aeruginosa PA14. Our analyses identify prot...
ORGANISM(S): Bacteria Pseudomonas sp. 
2022-09-06 | PXD035779 | Pride
Q-exactive hf Quorum sensing Ip-ms Bacteria 
ProteomicsMoonlighting chaperone 1 activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa
Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three intertwined quorum sensing systems control virulence of P. aeruginosa, with the rhl circuit playing the leading role in late and ...
ORGANISM(S): Pseudomonas aeruginosa PA14 
2023-03-11 | PXD038000 | Pride
Rhlr Pseudomonas aeruginosa Pqse Quorum sensing Lc-ms/ms 
GenomicsPqsE expands and differentially modulates the RhlR quorum sensing regulon in Pseudomonas aeruginosa
PqsE expands and differentially modulates the RhlR quorum sensing regulon in Pseudomonas aeruginosa
PRJNA826892 | ENA
TranscriptomicsPqsE expands and differentially modulates the RhlR quorum sensing regulon in Pseudomonas aeruginosa
While it is known that PqsE can stimulate the ability of RhlR to control some virulence factors, no data are available allowing clear discrimination of the PqsE and RhlR regulons. In this study, a P. aeruginosa PAO1 mutant strain with deletion of multiple QS elements and inducible expression of PqsE...
ORGANISM(S): Pseudomonas aeruginosa 
2022-05-17 | GSE200835 | GEO
UnknownProtein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa.
Not available
S-EPMC9600345 | biostudies-literature
UnknownPqsE Expands and Differentially Modulates the RhlR Quorum Sensing Regulon in Pseudomonas aeruginosa.
Not available
S-EPMC9241726 | biostudies-literature
TranscriptomicsPseudomonas aeruginosa PA14, pqsE and PQS
The Pseudomonas aeruginosa MvfR-dependent QS regulatory pathway controls the expression of key virulence genes; and is activated via the extracellular signals 4-hydroxy-2-heptylquinoline (HHQ) and 3,4-dihydroxy-2-heptylquinoline (PQS). Our findings reveal a multi-layered homeostatic regulation of PQ...
ORGANISM(S): Pseudomonas aeruginosa 
2009-07-17 | GSE17116 | GEO
GenomicsPseudomonas aeruginosa
Pseudomonas aeruginosa PA14, pqsE and PQS
PRJNA123657 | ENA
UnknownThe PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa.
Not available
S-EPMC9454246 | biostudies-literature
UnknownMoonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Not available
S-EPMC9715718 | biostudies-literature
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