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ProteomicsMC4 crosslinking of rhodopsin and GRK1 complex
G protein-coupled receptor (GPCR) kinases (GRKs) selectively phosphorylate agonist bound GPCRs, thereby switching the signal from G protein-dependent to arrestin-dependent pathways, including receptor internalization and downregulation. There are currently no high-resolution details known about how ...
ORGANISM(S): Bos taurus (Bovine) 
2021-07-15 | PXD019215 | Pride
Mc4 Grk1 Rhodopsin Crosslinking Gpcr Rhodopsin kinase 
ProteomicsProteome analysis of the retina from RhoQ344X/+ mouse
Retinal proteomes from wild-type and RhoQ344X mutant mice at postnatal day 35 were analyzed by label-free quantitative proteomics to understand proteomic change caused by the rhodopsin mutation.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-11-08 | MSV000093339 | MassIVE
UnknownAbnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase.
Not available
S-EPMC22360 | biostudies-literature
ProteomicsNetwork biology analysis of P23H rhodopsin interactome identifies protein and mRNA quality control mechanisms
Rhodopsin is essential for phototransduction, and many rhodopsin mutations cause heritable retinal degenerations. The P23H rhodopsin variant generates a misfolded rhodopsin protein that photoreceptors quickly target for degradation by mechanisms that are incompletely understood. To gain insight in...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-08-24 | MSV000090197 | MassIVE
UnknownStructures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Not available
S-EPMC8607881 | biostudies-literature
UnknownStructure of a monomeric variant of rhodopsin kinase at 2.5 A resolution.
Not available
S-EPMC3370896 | biostudies-literature
TranscriptomicsRNA-Seq of Xenopus laevis Retina after Crispr-mediated Rhodopsin depletion
In Xenopus laevis knocking out rhodopsin genes by crispr/Cas9 is a model of Retinitis pigmentosa. In late tadpole (permissive stages), glial Muller cells proliferate to support a regeneration response in the retina. However in early tadpole (refractory stages) the proliferative response is absent an...
ORGANISM(S): Xenopus laevis 
2025-02-02 | E-MTAB-13881 | biostudies-arrayexpress
UnknownA photochromic histidine kinase rhodopsin (HKR1) that is bimodally switched by ultraviolet and blue light.
Not available
S-EPMC3501036 | biostudies-literature
UnknownSubstrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1).
Not available
S-EPMC3422436 | biostudies-literature
UnknownStructures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation.
Not available
S-EPMC2376226 | biostudies-literature
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