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RNA-seq was performed in biological replicates (2 mice per group) of wild-type and lincRNA-EPS-/- BMDMs at 0, 2, and 6 hours after LPS treatment (100 ng/ml). RNA-seq libraries were prepared as described (Heyer et al., 2015). Briefly, ribosomal RNA (rRNA) was depleted using the Ribozero rRNA removal ...
ORGANISM(S): Mus musculus 
Background: Angioimmunoblastic T-cell lymphoma (AITL) is a malignancy with very poor survival outcome, in need of new more specific therapeutic regimen. The drivers of malignancy in this disease are CD4+ follicular helper T cells (Tfh). The metabolism of these malignant Tfh cells was not yet elucida...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-04 | PXD046786 | Pride
The unfolded protein response (UPR) is a key adaptive pathway that controls endoplasmic reticulum (ER) homeostasis. The UPR is transduced by three ER-resident proteins acting as sensors of ER homeostasis in the lumen of this compartment and triggering select downstream signaling pathways in the cyto...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD051657 | Pride
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