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ProteomicsData-independent acquisition protease-multiplexing enables increased proteome sequence coverage across multiple fragmentation modes
The use of multiple proteases has been shown to increase protein sequence coverage in proteomics experiments, but due to the additional sample preparation and analysis time required, it has not been widely adapted in routine proteomic workflows. While data-independent acquisition (DIA) has been prim...
ORGANISM(S): Homo sapiens (Human) 
2022-03-18 | PXD027242 | Pride
Dia Gluc Multiplexing Aspn 
ProteomicsThe microenvironment dictates glyco-immune surveillance via HSF1-mediated metabolism
Efforts to identify anti-cancer therapeutics are attempted with in vitro models that do not match the microenvironmental characteristics of human tissues. Using biocompatible hydrogels that mimic healthy or cancerous tissues and conventional or physiologically relevant culture medium, we systematica...
ORGANISM(S): Homo sapiens (Human) 
2026-04-10 | PXD044309 | Pride
Ecm Metabolism Glycosylation Lc-ms/ms Mechanopharmacology 
ProteomicsTax1bp1 enhances bacterial virulence and promotes inflammatory responses during Mycobacterium tuberculosis infection of alveolar macrophages
Crosstalk between autophagy, host cell death, and inflammatory host responses to bacterial pathogens enables effective innate immune responses that limit bacterial growth while minimizing coincidental host damage. Mycobacterium tuberculosis (Mtb) thwarts innate immune defense mechanisms in alveolar ...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-15 | PXD064244 | Pride
Immune defense . mycobacterium tuberculosis Lc-msms 
ProteomicsSelective RNA sequestration in P-bodies regulates cell identity
Post-transcriptional regulation is pivotal in guiding the gene expression programs that instruct cell fate decisions. Recent studies emphasize the significance of biomolecular condensates in modulating gene expression through RNA processing and translational control. However, the functional roles of...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD058827 | Pride
P-bodies Proteomics Stem cells 
ProteomicsThe Global Phosphorylation Landscape of SARS-CoV-2 Infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, has infected over 3 million people worldwide and caused over 200,000 deaths since it emerged in late 2019. There is an urgent need to develop therapies that can limi...
ORGANISM(S): Cercopithecus aethiops (Green monkey) (Grivet) 
2020-07-06 | PXD019113 | Pride
Sars-cov-2 Proteomics Vero-e6 Phosphoproteomics Coronavirus Covid-19 
ProteomicsMtruncatula - Stem, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 14.8, Coverage: 27
ORGANISM(S): 3880 
2016-00-00 | 2164794630 | PAXDB
ProteomicsMtruncatula - Root, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 13.0, Coverage: 29
ORGANISM(S): 3880 
2016-00-00 | 3047189613 | PAXDB
ProteomicsMtruncatula - Leaf, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 17.2, Coverage: 30
ORGANISM(S): 3880 
2016-00-00 | 3540523698 | PAXDB
ProteomicsMtruncatula - Flower, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 17.0, Coverage: 32
ORGANISM(S): 3880 
2016-00-00 | 2102073507 | PAXDB
ProteomicsMtruncatula - Seed, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 13.9, Coverage: 26
ORGANISM(S): 3880 
2016-00-00 | 1575946262 | PAXDB
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