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ATM is a serine/threonine protein kinase that is responsible for initiation of DNA repair of double-stranded breaks and is a therapeutic target in cancer. A lack of analytically robust and multiplexed assays has hampered mechanistic studies of action and determination of optimal, robust pharmacodyna...
ORGANISM(S): Homo sapiens (Human) 
2021-07-29 | PXD026103 | Pride
To see the role of SDCBP for protein recruitment into extracellular vesicle, we did comparative EV proteomic before and after SDCBP knockout.
ORGANISM(S): Homo sapiens (Human) 
2019-12-02 | PXD012321 | Pride
Immunotherapies are revolutionizing cancer care, producing durable responses and potentially cures in a subset of patients. However, response rates are low for most tumors, grade 3/4 toxicities are not uncommon, and our current understanding of tumor immunobiology is incomplete. While hundreds of im...
ORGANISM(S): Homo Sapiens 
2022-02-28 | PXD029167 | panorama
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