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TranscriptomicsRNA-seq of the brain of Nothobranchius furzeri at different time points
Background: Comparison of temporal gene expression profiles (www.jenage.de) The RNA-seq data comprises 5 age groups: 5,12,20,27,39 weeks 25 samples: 5 biological replicates for each age group
ORGANISM(S): Nothobranchius furzeri 
2014-07-29 | E-GEOD-52462 | biostudies-arrayexpress
GenomicsEpigenetics profiling of human BLaER1 pre-B cells transdifferentiation into macrophages
BLaER1 is a human B cell precursor leukemia cell line derived from the RCH-ACV cells. These cells are stably infected with a construct that overexpresses the transcription factor C/EBPa fused with the estrogen receptor hormone binding domain (ER) and GFP. Upon induction with beta-estradiol, C/EBP is...
ORGANISM(S): Homo sapiens 
2022-05-31 | E-MTAB-9825 | biostudies-arrayexpress
ProteomicsSpastin recovery in hereditary spastic paraplegia by preventing neddylation-dependent degradation
Hereditary Spastic Paraplegia (HSP) is a neurodegenerative disease most commonly caused by autosomal dominant mutations in the SPG4 gene encoding the microtubule severing protein spastin. We hypothesise that SPG4-HSP is attributable to reduced spastin function due to haploinsufficiency, thus therape...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2020-10-22 | PXD021945 | Pride
Ubiquitination Spastin Hipk2 Spg4-hsp Protesomal degradation 
ProteomicsCharacterization of extracellular vesicles from cell suspension 2 cultures of Coffea arabica L.
A protocol was developed for the isolation and characterization of extracellular vesicles (EVs) from Coffea arabica cell suspension cultures (CSC). The isolation method involved differential ultracentrifugation of the CSC filtrate, yielding two fractions: 100,000 g for 36 minutes (100k g) and 125,00...
ORGANISM(S): Coffea arabica (Arabian coffee) 
2026-02-16 | PXD071909 | Pride
Cell suspension cultures  coffea arabica  extracellular vesicles (evs)  morpho-34 metric traits  proteomics  unconventional protein secretion 
Transcriptomics4f-SAMMY-seq (Sequential Analysis of MacroMolecules Accessibility) and total RNA-seq data from prostate biopsies of 25 chemo-naïve patients (7 healthy biopsies and 18 tumor biopsies)
We used a groundbreaking epigenomic profiling technique developed in our laboratory, the 4f-SAMMY-seq, along with RNA-seq on 7 healthy biopsies and 18 prostate tumor biopsies. Our study represents the first direct examination of chromatin organization in patient-derived prostate biopsies. Leveraging...
ORGANISM(S): Homo sapiens 
2025-08-21 | E-MTAB-14226 | biostudies-arrayexpress
GenomicsZFP57 recognizes multiple and closely spaced sequence motif variants to maintain repressive epigenetic marks in mouse embryonic stem cells
In mouse embryonic stem cells SNPs disrupting closely-spaced hexanucleotide motifs are associated with lack of ZFP57 binding and H3K9me3 enrichment. Examination of ZFP57-KAP1 allele-specific binding in two lines of mouse embryonic stem cells JB1 and BJ1 generated from F1 hybrids derived from JF1 x B...
ORGANISM(S): Mus musculus 
2015-11-06 | E-GEOD-74757 | biostudies-arrayexpress
GenomicsChIPseq of enterocytes of the jejunum from transgene C57BL/6 mice harboring a CKIαΔgut knock-out
ChIPseq of enterocytes of the jejunum from transgene C57BL/6 mice to assess the effects of a CKIαΔgut knock-out in the jejunum and a CKIαΔgut/p53 double knock-out. In addition, enterocytes expressing a mutant p53 (R172H) in combination with CKIαΔgut knockout were analyzed.
ORGANISM(S): Mus musculus 
2020-02-25 | E-MTAB-7858 | biostudies-arrayexpress
UnknownSimvastatin in Critically Ill Patients with Covid-19.
Not available
S-EPMC10755839 | biostudies-literature
UnknownChanges in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study.
Not available
S-EPMC7926077 | biostudies-literature
UnknownBlood culture practices and microbiological capacity for sepsis diagnostics in Europe (2021-2022): a cross-sectional analysis of the European Sepsis Care Survey.
Not available
S-EPMC12771334 | biostudies-literature
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