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ProteomicsIdentification of interaction partners of novel polyacetylene
To elucidate molecular interaction partners of a novel plant-derived polyacetylene, we used a biotin-labelled polyacetylene in two cell lines (HEK293 and HepG2) and performed biotin-pulldown assays and proteomic analyses via LC-MSMS.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD037671 | Pride
Lc-msms Biotin-label compound Human cell lines 
ProteomicsIdentification of human GRHL1 interactors and post-translational modifications by LC-MS/MS
Aim of the project was to identify interactors and post-translational modifications of recombinant 3xFLAG-6xHis-tagged human GRHL1, tandem-affinity purified from isolated HEK293 nuclei treated with DMSO as control or with the phytochemical papaverine.
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD021768 | Pride
Interactors Transcription factor Post-translational modification Grhl1 Lc-ms/ms 
ProteomicsIdentification of biotinylated papaverine interactors from HEK293 total cell extract by LC-MS/MS
Aim of the project was to identify interactors of the phytochemical papaverine, modified with a biotin moiety, from HEK293 total cell extract by LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD021808 | Pride
Interactors Compound Biotinylation Papaverine Lc-ms/ms 
UnknownFrataxin activates mitochondrial energy conversion and oxidative phosphorylation.
Not available
S-EPMC17325 | biostudies-literature
UnknownRedox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A.
Not available
S-EPMC7096751 | biostudies-literature
UnknownGrainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan.
Not available
S-EPMC8748497 | biostudies-literature
TranscriptomicsImpaired Insulin-/IGF1-Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS-Signal
Transcriptome profiling of three models with impaired insulin/IGF1 signaling. 1. Deep sequencing of endogenous mRNA from Caenorhabditis elegans N2 var. Bristol (wildtype) and daf-2(e1370) mutant; 2. Deep sequencing of endogenous mRNA from murine embryonic fibroblasts (MEF) wildtype and irs1-/- kno...
ORGANISM(S): Caenorhabditis elegans 
2012-02-25 | E-GEOD-36041 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence and absence of arsenite
Background: Arsenite is one of the most toxic chemical substances known and is assumed to exert detrimental effects on viability even at lowest concentrations. By contrast and unlike higher concentrations, we here find that exposure to low-dose arsenite promotes growth of cultured mammalian cells. I...
ORGANISM(S): Caenorhabditis elegans 
2013-04-23 | E-GEOD-46257 | biostudies-arrayexpress
ModelsGebauer2016 - Genome-scale model of Caenorhabditis elegans metabolism (without bacteria)
Gebauer2016 - Genome-scale model of Caenorhabditis elegans metabolism (without bacteria) This model is one of the two versions of ElegCyc presented in the paper. It describes the metabolism of a worm raised in a medium without bacteria. This model is described in the article: A Genome-Sca...
2017-04-20 | MODEL1704200000 | BioModels
ModelsGebauer2016 - Genome-scale model of Caenorhabditis elegans metabolism (with bacteria)
Gebauer2016 - Genome-scale model of Caenorhabditis elegans metabolism (with bacteria) This model is one of the two versions of ElegCyc presented in the paper. It describes the metabolism of a worm raised in a medium with bacteria This model is described in the article: A Genome-Scale Data...
2017-04-20 | MODEL1704200001 | BioModels
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