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ProteomicsRNA interactome capture identifies key proteins for herpesviral gene expression
The primary mRNA sequence determines its secondary structure and the repertoire of interacting RNA binding proteins (RBPs). The resulting mRNA ribonucleoprotein complex (mRNP) then influences all stages of the life of an mRNA. Here, we determined the mRNP composition of individual Kaposi Sarcoma Her...
ORGANISM(S): Homo sapiens (Human) Human gammaherpesvirus 8 
2026-01-23 | PXD056253 | Pride
Kshv Au-rich sequences Srsf3 Rna-binding-proteins Rna interactome capture Rna stability Codon optimization Herpesviral gene expression Rbps Lytic transcripts Orf57 
TranscriptomicsGWAS region focused capture-HiC of primary melanocytes from five human donors
Capture-HiC was conducted to map chromatin interactions at all melanoma GWAS identified risk-associated regions across five individual primary human melanocyte cultures. Capture-HiC baits were designed by Arima Genomics (San Diego, CA, 2x tiling, least stringent masking, XTHSBoosting) to obtain an A...
ORGANISM(S): Homo sapiens 
2025-04-24 | E-MTAB-15079 | biostudies-arrayexpress
ProteomicsIdentifying lncRNA-protein interactions in hematopoietic progenitor cells by hybridization capture and mass spectrometry
Long non-coding RNAs (lncRNAs) exert regulatory functions in a wide spectrum of biological contexts, and certain regulatory functions involve the formation of RNA-protein complexes. Discovering the structure/function of these complexes may unveil important functional insights. The DDX41 gene encodin...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-17 | PXD062695 | Pride
Lncrna  lncrna-protein interaction  hematopoiesis  mass spectrometry  proteomics  hybridization capturelncrna  lncrna-protein interaction  hematopoiesis  mass spectrometry  proteomics  hybridization capture 
TranscriptomicsMelampsora larici-populina gene expression in different tissues of uredinia
Laser Capture Microdissection (LCM) was used for expression analysis of three contrasted fungal tissues of uredinia corresponding respectively to spores and sporogenous hyphae, fungal structures in the spongy mesophyll and fungal infection structures in the palisade mesophyll. The array probes were ...
ORGANISM(S): Melampsora laricis-populina 
2010-07-22 | E-GEOD-21487 | biostudies-arrayexpress
TranscriptomicsExpression data from LCM captured prostate cancer cells
The prostate represents a complex mix of cell types and there is a need to analyze distinct cell populations to better understand their potential interactions. This study of cell-type specific gene expression patterns will contribute to understanding of how tumor epithelial cells may be affected by...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-20758 | biostudies-arrayexpress
GenomicsPromoter Capture-HiC in Ring1a KO and Ring1a/b dKO mouse ES cells
Genome organization influences transcriptional regulation by facilitating interactions between gene promoters and distal regulatory elements. To analyse distal promoter contacts mediated by the PRC1 complex we used Capture Hi-C (CHi-C) to enrich for promoter-interactions in a HiC library in Ring1a K...
ORGANISM(S): Mus musculus 
2015-08-01 | E-MTAB-3109 | biostudies-arrayexpress
TranscriptomicsThe Extracellular RNA Quality Control (exRNAQC) study: RNA Exome sequencing of interaction study (exRNAQC017)
Study to detect possible interactions between blood collection tubes and RNA purification methods on extracellular RNA (exRNA) sequencing. Different combinations of blood collection tubes (3 in total), time intervals between blood draw and downstream processing (immediate (T0), after 4 hours (T4), a...
ORGANISM(S): Homo sapiens 
2022-12-25 | E-MTAB-12541 | biostudies-arrayexpress
ProteomicslncRNA-protein interactions in hematopoietic progenitor cells by hybridization capture and mass spectrometry
Long non-coding RNAs (lncRNAs) exert regulatory functions in a wide spectrum of biological contexts, and certain regulatory functions involve the formation of RNA-protein complexes. Discovering the structure/function of these complexes may unveil important functional insights. The DDX41 gene encodin...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-13 | PXD055956 | Pride
Lc/ms Mouse Hypr-ms Rna-protein interaction 
TranscriptomicsChromatin interaction map of promoters in iPSC-derived human cardiomyocytes using capture in situ Hi-C
We generated an interaction map using capture in situ Hi-C in human iPSC-derived cardiomyocytes Differentiation of cardiomyocytes from iPSC followed by capture in situ Hi-C
ORGANISM(S): Homo sapiens 
2016-02-22 | E-GEOD-77266 | biostudies-arrayexpress
TranscriptomicsCombined Use of Laser Capture Microdissection and Microarray Analysis Identifies Locally Expressed Disease-Related Genes in Focal Regions of Psoriasis Vulgaris Skin Lesions
In this study, we sought to establish the usefulness of LCM on cDNA microarray analysis. We reported that LCM samples improved the sensitivity of detection of differentially expressed genes over conventional bulk tissue analysis. We also provided the new information of chemokine and its receptor int...
ORGANISM(S): Homo sapiens 
2012-01-30 | E-GEOD-26866 | biostudies-arrayexpress
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