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Genomicscircular RNAs in RNasek deficient MEFs
circular RNAs in RNasek deficient MEFs
PRJNA1392462 | ENA
ProteomicsThe V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation
Autophagy is a finely orchestrated process required for the lysosomal degradation of cytosolic components. The final degradation step is essential for clearing autophagic cargo and recycling macromolecules. Using a CRISPR/Cas9-based screen, we identify RNAseK, a highly conserved transmembrane protei...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-02 | PXD042079 | Pride
Dia-ms Autophagosome degradation Rnasek Lysosome 
Genomicscircular RNAs in RNASEK depleted cells
circular RNAs in RNASEK depleted cells
PRJNA1392457 | ENA
Genomicscircular RNAs in RNasek deficient MEFs
Circular RNA microarray under Rnasek depletion.
ORGANISM(S): Mus musculus 
2026-02-24 | GSE314686 | GEO
Genomicscircular RNAs in RNASEK depleted cells
Circular RNA microarray under RNASEK depletion.
ORGANISM(S): Homo sapiens 
2026-02-24 | GSE314687 | GEO
UnknownThe V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation.
Not available
S-EPMC11374810 | biostudies-literature
UnknownFish Paralog Proteins RNASEK-a and -b Enhance Type I Interferon Secretion and Promote Apoptosis.
Not available
S-EPMC8645942 | biostudies-literature
ProteomicsRibonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules
Circular RNAs (circRNAs) accumulate with age, but their functional impact on aging remains elusive. In this study, we reveal a mechanism by which ribonuclease κ (RNASEK) prevents age-dependent circRNA accumulation by promoting its degradation. Through a genetic screen targeting ribonucleases, we ide...
ORGANISM(S): Caenorhabditis Elegans 
2026-01-15 | PXD073097 |
UnknownAnalysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression.
Not available
S-EPMC4747458 | biostudies-literature
ProteomicsA lysosomal delivery mechanism required for autophagosome degradation
Autophagy is a finely orchestrated process required for the lysosomal degradation of cytosolic components. The final degradation step is essential for clearing autophagic cargo and recycling macromolecules. We identified a highly conserved transmembrane protein named RNAseK as a novel regulator of a...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-05 | PXD042727 | Pride
Autophagy 
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