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TranscriptomicsImproved transcription and translation with L-leucine stimulation of mTORC1
Roberts syndrome (RBS) is a human developmental disorder caused by mutations in the cohesin acetyltransferase ESCO2. We previously reported that mTORC1 was inhibited and overall translation was reduced in RBS cells. Treatment of RBS cells with L-leucine partially rescued mTOR function and protein sy...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-64962 | biostudies-arrayexpress
TranscriptomicsGenome-wide replication analysis of a yeast eco1 mutant by deep sequencing.
Eco1 is the acetyltransferase that establishes sister-chromatid cohesion during DNA replication. Budding yeast with an eco1 mutation that genocopies Roberts syndrome displaysreduced ribosomal DNA (rDNA) transcription and a transcriptional signature of starvation. Weshow that deleting FOB1, a gene en...
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-03 | E-GEOD-54742 | biostudies-arrayexpress
UnknownAlternating oligo(o,p-phenylenes) via ruthenium catalyzed diol-diene benzannulation: orthogonality to cross-coupling enables de novo nanographene and PAH construction.
Not available
S-EPMC6194800 | biostudies-literature
TranscriptomicsQuantitative time-course profiling of Plasmodium falciparum transcripts and proteins throughout the 48-hour intraerythrocytic developmental cycle
Quantitative studies of the P. falciparum transcriptome have shown that the tightly controlled progression of the parasite through the intraerythrocytic developmental cycle (IDC) is accompanied by a continuous gene expression cascade where most expressed genes exhibit a single transcriptional peak. ...
ORGANISM(S): Plasmodium falciparum 
2011-06-07 | E-GEOD-24416 | biostudies-arrayexpress
TranscriptomicsPAO1 gene expression at 22M-BM-0C and 37M-BM-0C in Lysogeny broth
Pseudomonas aeruginosa strain PAO1 was grown at 22M-BM-0C and 37M-BM-0C in Lysogeny broth (LB) and RNA was hybridized on the Affymetrix P. aeruginosa chip. PAO1 was grown in triplicate in Lysogeny broth at 22M-BM-0C or 37M-BM-0C. Total RNA from each sample was pooled and amplified then assayed in t...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2014-01-01 | E-GEOD-51409 | biostudies-arrayexpress
TranscriptomicsPAHM4 vs PAO1 37C LB
Pseudomonas aeruginosa strains PAHM4 and PAO1 were grown at 37C on LB and RNA was hybridized on the Affymetrix P. aeruginosa chip to compare transcript differences from a BQ isolate to a well characterized wound isolate. Strains PAHM4 and PAO1 were grown in triplicate. Total RNA from each sample wa...
ORGANISM(S): Pseudomonas aeruginosa PAHM4 
2012-10-01 | E-GEOD-40461 | biostudies-arrayexpress
UnknownInfluence of dietary fat type on benzo(a)pyrene [B(a)P] biotransformation in a B(a)P-induced mouse model of colon cancer.
Not available
S-EPMC3904801 | biostudies-literature
UnknownP-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin.
Not available
S-EPMC1853301 | biostudies-literature
UnknownComplete genome assembly and methylome dissection of Methanococcus aeolicus PL15/H p.
Not available
S-EPMC10113651 | biostudies-literature
UnknownStructural implications of novel diversity in eucaryal RNase P RNA.
Not available
S-EPMC1370759 | biostudies-literature
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