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GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
MetabolomicsUntargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases. A more accurate risk stratification remains a key point in the study of NB and the availability of...
2023-07-14 | MTBLS4294 | MetaboLights
UnknownStructures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes.
Not available
S-EPMC7034192 | biostudies-literature
ProteomicsProteomics analysis of human islets treated with IL-1b and IFN-g
Human islets were treated with IL-1b and IFN-g for 24h, digested with trypsin, multiplexed with TMT-10, fractionated by high pH reverse-phase chromatography and analyzed by tandem LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2019-10-25 | PXD009131 | Pride
Proteomics Tmt-10 Cytokines Human islets Type 1 diabetes Cell death 
UnknownG-protein activation by a metabotropic glutamate receptor.
Not available
S-EPMC8822903 | biostudies-literature
ProteomicsProteomics analysis of EndoC-betaH1 cells treated with IL-1b and IFN-g
EndoC-betaH1 cells were treated with IL-1b and IFN-g for 48h, digested with trypsin, multiplexed with TMT-10, fractionated by high pH reverse-phase chromatography and analyzed by tandem LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2019-09-26 | PXD011902 | Pride
Beta cells Proteomics Tmt-10 Cytokines Type 1 diabetes Cell death 
UnknownStructure of a Signaling Cannabinoid Receptor 1-G Protein Complex.
Not available
S-EPMC6461403 | biostudies-literature
UnknownHexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56.
Not available
S-EPMC10289240 | biostudies-literature
UnknownSynthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands.
Not available
S-EPMC8152782 | biostudies-literature
UnknownDifferential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells.
Not available
S-EPMC105379 | biostudies-literature
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