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ProteomicsHuman Plasma from non-Hispanic White and African American Sepsis Survivors and Non-Survivors with Primary Intra-Abdominal Infection LC-MS/MS
This study examined global proteomic changes in blood plasma from non-Hispanic White and African American sepsis patients with primary intra-abdominal infection using LC-MS/MS on a Q-Exactive HF. Proteins were quantified in the LC-MS/MS experiments using Tandem Mass Tags 16-plex (TMTpro).
ORGANISM(S): Homo sapiens (Human) 
2022-09-13 | PXD030476 | Pride
Human Sepsis Tmt Plasma Lc-ms/ms 
ProteomicsKinome profiling: cabozantinib treatment in a mouse model of plexiform neurofibroma
Neurofibromatosis type 1 (NF1) is the most common autosomal dominant disorder, affecting 1 in 3,500 individuals worldwide and predisposing to cancer. Germline mutations in the NF1 gene, encoding the p21Ras GTPase-activating protein (GAP) neurofibromin, are the underlying cause for NF1. Somatic inact...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-18 | PXD019005 | Pride
Receptor tyrosine kinase Nf1 Xl184 
UnknownA systematic review and meta-analysis of community and primary-care-based hepatitis C testing and treatment services that employ direct acting antiviral drug treatments.
Not available
S-EPMC6819346 | biostudies-literature
ProteomicsSex differences in the ventral tegmental area and nucleus accumbens proteome at baseline and following nicotine exposure
Sex differences in behaviors relevant to nicotine addiction have been observed in rodent models and human subjects. Behavioral, imaging and epidemiological studies also suggest underlying sex differences in mesolimbic dopamine signaling pathways. In this study we evaluated the proteome in the ventra...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-28 | PXD023859 | Pride
Sex Nicotine exposure Mouse Vta Nac 
UnknownReducing the standard serving size of alcoholic beverages prompts reductions in alcohol consumption.
Not available
S-EPMC6099514 | biostudies-literature
UnknownProteomics reveals age-related differences in the host immune response to sepsis.
Not available
S-EPMC3976438 | biostudies-literature
UnknownAccelerating clinical development of a live attenuated vaccine against Salmonella Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a novel oral vaccine using a human challenge model of Salmonella Paratyphi A infection in healthy adult volunteers.
Not available
S-EPMC10230971 | biostudies-literature
UnknownA Prospective Cohort Protocol for the Remnant Investigation in Sepsis Study.
Not available
S-EPMC10833627 | biostudies-literature
UnknownPhase II multicentre double-blind randomised controlled trial of a Bivalent VaccInation against Salmonella Typhi and Paratyphi A (BiVISTA) using a controlled human infection model of paratyphoid A infection: study protocol.
Not available
S-EPMC12853460 | biostudies-literature
UnknownGenetic activation of ERK2 recapitulates core neurodevelopmental features of Rasopathy syndromes in mice.
Not available
S-EPMC12724492 | biostudies-literature
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