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To assess the effect of CD25 (Il2ra) knockout on signaling in pre-B leukemia, pre-B cells from CD25-floxed mouse bone marrow were grown ex-vivo with IL-7 and transformed with BCR-ABL1, before treatment with 4-OHT to induce CD25 KO. Phosphoproteomics was performed and differential phosphosites analys...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD038996 | Pride
Our studies in Salmonella Typhimurium (S. Typhimurium)-infected cells indicate that TFEB has a non-transcriptional, cytosolic function in addition to its well-characterized role as a transcription factor in regulating autophagy and lysosome biogenesis. An unbiased proteomics approach revealed that T...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD013758 | Pride
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