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TranscriptomicsA human genome-wide screen for regulators of clathrin-coated vesicle formation
Clathrin-mediated endocytosis is essential for a wide range of cellular functions. We used a multi- step siRNA-based screening strategy to identify novel regulators of the first step of clathrin- mediated endocytosis, formation of clathrin-coated vesicles (CCVs) at the plasma membrane. A primary gen...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-39954 | biostudies-arrayexpress
ProteomicsThe role of the AP-1 adaptor complex in outgoing and incoming membrane trafficThe role of the AP-1 adaptor complex in outgoing and incoming membrane traffic
The AP-1 adaptor complex is found in all eukaryotes, but it has been implicated in different pathways in different organisms. To look directly at AP-1 function, we generated stably transduced HeLa cells co-expressing tagged AP-1 and various tagged membrane proteins. Live cell imaging showed that AP-...
ORGANISM(S): Homo sapiens (Human) 
2024-04-03 | PXD050449 | Pride
Ap-1 Silac Ip-ms Trafficking 
GenomicsHomo sapiens
A human genome-wide screen for regulators of clathrin-coated vesicle formation
PRJNA172162 | ENA
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