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TranscriptomicsS. aureus gene expression following growth in media containing oleic acid
S. aureus response to exogenous fatty acid (oleic acid) Gene expression profiles were generated by microarray analysis of S. aureus cells grown in media without or with oleic aicd Comparison of expression profiles after growth of S. aureus in exogenous fatty acid S. aureus was grown in media with an...
ORGANISM(S): Staphylococcus aureus subsp. aureus RN4220 
2012-12-21 | E-GEOD-36231 | biostudies-arrayexpress
TranscriptomicsResponse of Escherichia coli to acetate concentration during growth on glucose
E. coli MG1655 was grown on M9 minimal medium supplemented with 15mM glucose and either 0, 10, 50 or 100 mM acetate. Transcriptomic analysis from exponential growing cells was performed using Agilent microarray A-MEXP-2232. This work was done with the help of students during practicals. Consequentl...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2020-08-21 | E-MTAB-9086 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of brains from honey bees of different ages, subspecies and host colony environment
Expression profiling of honey bee brains as a function of age, genotype (subspecies differences) and environment (host colony)
ORGANISM(S): Apis mellifera 
2007-04-25 | E-TABM-149 | biostudies-arrayexpress
TranscriptomicsChIP-on-chip of OmpR binding in Salmonella enterica serovar Typhimurium strain SL1344 and E.scherichia coli strain CSH50 at pH 7 and pH 4.5 including analysis of OmpR binding in SL1344 in the absence and presence of novobiocin (25 M-NM-
OmpR is a DNA binding protein belonging to the OmpR/EnvZ two component system. This system is known to sense changes in osmolarity in Escherichia coli. Recently, OmpR in Salmonella enterica serovar Typhimurium was found to be activated by acidic pH and DNA relaxation. In this study, ChIP-on-chip wa...
ORGANISM(S): Escherichia coli K-12 
2014-03-27 | E-GEOD-49914 | biostudies-arrayexpress
TranscriptomicsSMF-ONT S2 clamp RNAi knockdown
Collection of 2 biological replicates of SMF-ONT performed in S2 cell incubated for 72hrs with RNAi targeting Clamp or LacZ (ctrl) transcripts. The footprinting protocol was adapted from Kleinendorst and Barzaghi et al., 2021 and optimised for long-read sequencing and high weight DNA extraction. In...
ORGANISM(S): Drosophila melanogaster 
2026-08-04 | E-MTAB-17018 | biostudies-arrayexpress
TranscriptomicsImpact of gut microbiota on m6A/m epitranscriptomic mRNA modification in different host tissues
In this study we performed MeRIP-Seq to study N6-methyl adenosine (m6A) and and N6,2′ -O-dimethyladenosine (m6Am) modification of mRNA. We investigated the effect of the microbiota on the transcriptome and epitranscriptomic modifications in murine liver and cecum. We compared m6A/m modification prof...
ORGANISM(S): Mus musculus 
2020-02-12 | E-MTAB-6560 | biostudies-arrayexpress
GenomicsChIP-seq analyses of the Aspergillus fumigatus SREBP SrbA
The Aspergillus fumigatus sterol regulatory element binding protein (SREBP) SrbA belongs to the basic Helix-Loop-Helix (bHLH) family of transcription factors and is crucial for antifungal drug resistance and virulence. The latter phenotype is especially striking, as loss of SrbA results in complete...
ORGANISM(S): Aspergillus fumigatus 
2014-10-03 | E-GEOD-61974 | biostudies-arrayexpress
TranscriptomicsPhenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice [MeDIP array].
Evidence suggests that epigenetic perturbations are involved in the adverse effects associated with some drugs and toxicants, including certain classes of non-genotoxic carcinogens. Such epigenetic changes (altered DNA methylation and covalent histone modifications) may take place at the earliest st...
ORGANISM(S): Mus musculus 
2011-12-16 | E-GEOD-34462 | biostudies-arrayexpress
TranscriptomicsPotential of Neuropeptide PACAP38 Therapy for Brain Ischemia: Insights from Bioinformatics Analysis of the High-throughput DNA Microarray Analyses Data in PMCAO Mouse Model using Ischemic Core and Penumbra Transcriptomic Data
Permanent middle cerebral artery occlusion (PMCAO) mouse model has been established and used by our group with a focus on systematically investigating effects of the neuropeptide pituitary adenylate-cyclase activating polypeptide (PACAP38) on the ischemic brain. Using an intracerebroventrically PACA...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-67421 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Twist protein during embryonic development in Drosophila
Genomewide mapping of Drosophila Twist protein binding during embryonic development. Two consecutive timepoints (2-4 and 4-6 hrs after egg-laying) were assayed in four independent repeats each. Two different antibodies were used to precipitate the Twist protein. Additionally, preimmune-serum was use...
ORGANISM(S): Drosophila melanogaster 
2007-03-28 | E-TABM-159 | biostudies-arrayexpress
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