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MetabolomicsGNPS-Passive accumulation of alkaloids in non-toxic frogs challenges paradigms of the origins of acquired chemical defenses
Paper Title: Passive accumulation of alkaloids in non-toxic frogs challenges paradigms of the origins of acquired chemical defenses. Author List; Rebecca D Tarvin, Jeffrey L Coleman, David A Donoso, Mileidy Betancourth-Cundar, Karem Lopez-Hervas, Kimberly S Gleason, J Ryan Sanders, Jacqueline M Smit...
ORGANISM(S): Multiple Frog Species 
MSV000095866 | GNPS
TranscriptomicsISR target genes in the liver of either LFD and HFD-treated Alb::GC mice and AP20187-treated TTR::Fv2E-PERK mice
The molecular mechanisms linking the stress of unfolded proteins in the endoplasmic reticulum (ER stress) to glucose intolerance in obese animals are poorly understood. In this study enforced expression of a translation initiation 2alpha (eIF2a)-specific phosphatase, GADD34, was used to selectively ...
ORGANISM(S): Mus musculus 
2011-12-23 | E-GEOD-11210 | biostudies-arrayexpress
TranscriptomicsISR target genes in the liver of mock-injected and AP20187-treated mice of wildtype and Atf4-/- genotype
The molecular mechanisms linking the stress of unfolded proteins in the endoplasmic reticulum (ER stress) to glucose intolerance in obese animals are poorly understood. In this study enforced expression of a translation initiation 2α (eIF2α)-specific phosphatase, GADD34, was used to selectively comp...
ORGANISM(S): Mus musculus 
2011-12-23 | E-GEOD-11116 | biostudies-arrayexpress
ProteomicsYoung and aged T cells LC-MS/MS
Naïve T cells (CD4+CD62LhiCD44loCD25-) were purified from spleens of young (2 months; n=3) and aged (22 months; n=3 pools of five mice) mice and were either frozen or activated for 24 hrs.
ORGANISM(S): Mus musculus (Mouse) 
2025-10-08 | PXD067102 | Pride
Heme Aging Mouse Lymph nodes Spleen 
UnknowneDNA-Mediated Cutaneous Protection Against UVB Damage Conferred by Staphylococcal Epidermal Colonization.
Not available
S-EPMC8068790 | biostudies-literature
GenomicsCargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers
Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers
PRJNA665693 | ENA
UnknownEvidence for the weakly coupled electron mechanism in an Anderson-Blount polar metal.
Not available
S-EPMC6642157 | biostudies-literature
TranscriptomicsTranscription profiling of Integrated Stress Response induced by tunicamycin or following AP20187 induced dimerization of a Fv2E-PERK chimera in wildtype cells and cells carrying mutations in key ISR signaling molecules.
Comparison of genes induced during activation of the Integrated Stress Response by tunicamycin or following AP20187 induced dimerization of a Fv2E-PERK chimera in wildtype cells and cells carrying mutations in key ISR signaling molecules.
ORGANISM(S): Mus musculus 
2007-12-15 | E-GEOD-700 | biostudies-arrayexpress
TranscriptomicsTemporal transcriptional profiling of polyamine-depleted NIH3T3 cells
Polyamines are absolutely required for cell growth and proliferation. While polyamine depletion results in reversible cell cycle arrest, the actual mechanism of growth inhibition is still obscure. This work aimed at determining the cellular processes affected by reduction in the intracellular polyam...
ORGANISM(S): Mus musculus 
2012-09-11 | E-GEOD-36445 | biostudies-arrayexpress
TranscriptomicsFL5.12 Bfl-1DC/p53DD-derived splenic tumors compared to the parental FL5.12 Bfl-1DC/p53DD cell line
The antiapoptotic Bcl-2 family member Bfl-1 is upregulated in many human tumors in which NF-kB is implicated, and contributes significantly to tumor cell survival and chemoresistance. We previously found that NF-kB induces transcription of bfl-1, and that the Bfl-1 protein is also regulated by the u...
ORGANISM(S): Mus musculus 
2010-03-23 | E-GEOD-18204 | biostudies-arrayexpress
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