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TranscriptomicsHIF orchestrated metabolic shift confers protection against Acute Kidney Injury (AKI)
Renal hypoxia is widespread in acute kidney injury (AKI) of various aetiologies. Hypoxia adaptation, conferred through the hypoxia-inducible factor (HIF), appears to be insufficient. Here we show that HIF activation in renal tubules through Pax8-rtTA-based inducible knockout of von Hippel-Lindau pro...
ORGANISM(S): Mus musculus 
2013-09-05 | E-GEOD-44925 | biostudies-arrayexpress
UnknownExome sequencing in 38 patients with intracranial aneurysms and subarachnoid hemorrhage.
Not available
S-EPMC7419486 | biostudies-literature
ProteomicsLoss of the mechanistic target of rapamycin complexes 1 (mTORC1) causes a lethal alpha-1 antitrypsin deficiency associated liver disease
Alpha1-antitrypsin (AAT) mutations cause retention of the otherwise secreted protein and lead to the proteotoxic AAT deficiency (AATD)-related liver disease (AATD-LD). As mechanistic target of rapamycin (mTOR) is a key coordinator of proteostasis, we studied its role in AATD-LD. PiZ mice overexpress...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD061881 | Pride
Mouse Lc-ms Serum Liver Spatial Proteome 
UnknownOutcomes of a Delirium Prevention Program in Older Persons After Elective Surgery: A Stepped-Wedge Cluster Randomized Clinical Trial.
Not available
S-EPMC8674802 | biostudies-literature
ProteomicsM.tuberculosis - Whole organism, absolute concentration (Schubertetal,cellhostmicrobe2014)
abundance based on absolute concentration, Interaction consistency score: 1.0, Coverage: 46
ORGANISM(S): 83332 
2014-00-00 | 2118471723 | PAXDB
UnknownResuscitation Outcomes Consortium-Amiodarone, Lidocaine or Placebo Study (ROC-ALPS): Rationale and methodology behind an out-of-hospital cardiac arrest antiarrhythmic drug trial.
Not available
S-EPMC4014351 | biostudies-literature
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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