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UnknownFirst-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287427).
Not available
S-EPMC6804811 | biostudies-literature
TranscriptomicsTranscription profiling of mouse liver treated with phenobarbital and fed a high cholesterol diet an
High cholesterol diet and xenobiotic treatment induce changes in cholesterol homeostasis and drug metabolism. Mice were either 7 days on high cholesterol diet or were treated with phenobarbital. Liver samples were anayzed using Affymetrix GeneChip MOE430A. Experiment Overall Design: One group of mic...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6721 | biostudies-arrayexpress
TranscriptomicsDiet and phenobarbital affect cholesterol homeostasis and drug metabolism
High cholesterol diet and xenobiotic treatment induce changes in cholesterol homeostasis and drug metabolism. Mice were either 7 days on high cholesterol diet or were treated with phenobarbital. Liver samples were analyzed using Sterolgene v0 cDNA microarrays. Sterolgene microarray is a tool designe...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-6447 | biostudies-arrayexpress
Proteomicsvaccination protects against COVID-associated pulmonary fibrin deposition
Our recent work showed COVID BALF from vaccinated individuals contained significantly lower concentration of fibrinogen and prothrombin, suggesting a potential benefit of vaccination being lower risk of fibrin clotting and acute lung injury. As our previous mass spec-based proteomic ID approach show...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD066557 | Pride
Fibrin clotting Bal Covid Pulmonary disease Bronchi alveolar lavage Sars-covid-2 
UnknownAdverse birth outcomes of adolescent and young adult women diagnosed with cancer during pregnancy.
Not available
S-EPMC10248853 | biostudies-literature
TranscriptomicsHigh-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
The ability to perturb genes in human cells is crucial for elucidating gene function and holds great potential for finding therapeutic targets for diseases such as cancer. To extend the catalog of human core and context- dependent fitness genes, we have developed a high-complexity second-generation ...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75189 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of leaves of Arabidopsis thaliana Col-0 plants exposed to volatile pinenes (treatment) or hexane (control)
Volatile organic compounds (VOCs) may play a role in systemic acquired resistance (SAR), a salicylic acid (SA)-associated, broad-spectrum immune response in systemic, healthy tissues of locally infected plants. Four-to-five-week-old plants were exposed for three days to a mixture of volatile pinenes...
ORGANISM(S): Arabidopsis thaliana 
2017-06-01 | E-MTAB-5475 | biostudies-arrayexpress
UnknownRisk for Heart Failure and Atrial Fibrillation Across the Lifespan for Carriers of the Amyloidogenic p.V142I <i>TTR</i> Variant.
Not available
S-EPMC12313181 | biostudies-literature
TranscriptomicsAltered glycogen metabolism causes hepatomegaly following an Atg7 deletion
Autophagy is a lysosomal degradation process involved in the turnover of organelles or other cell constituents, in providing sources for energy production under starving conditions, and in cell metabolism. A key protein in the macroautophagic machinery is the autophagy related protein (Atg) 7. Const...
ORGANISM(S): Mus musculus 
2016-07-12 | E-MTAB-4389 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver exposed to 24h cytokine starvation vs. treatment with TNF alpha
Pathogenesis of atherosclerosis results from the interactions between disrupted lipid homeostasis and immune response but the molecular bridges between the major players are still a matter of controversy. We investigated the systemic effect of inflammatory cytokine tumor necrosis factor alpha (TNF-Î...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6317 | biostudies-arrayexpress
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