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Gene expression of tumors derived from sorted Brca1/p53-deficient cell subpopulations
ORGANISM(S): Mus musculus 
We have studied in vivo responses of spontaneous Brca1- and p53-deficient mouse mammary tumors to treatment with doxorubicin, docetaxel or cisplatin.
ORGANISM(S): Mus musculus 
Using gene expression profiling of mammary tumors generated in a mouse model for BRCA1-associated breast cancer we have searched for markers that correlate with response to the anti-cancer drugs docetaxel or cisplatin. To validate the results, the analysis was done on 2 different platforms (39K Mous...
ORGANISM(S): Mus musculus 
Using gene expression profiling of mammary tumors generated in a mouse model for BRCA1-associated breast cancer we have searched for markers that correlate with response to the anti-cancer drugs docetaxel or cisplatin. To validate the results, the analysis was done on 2 different platforms (39K Mous...
ORGANISM(S): Mus musculus 
Analysis of plasma membrane enriched protein fractions from NAA60-proficient or deficient mouse mammary tumor cells.
ORGANISM(S): Mus musculus (Mouse) 
2025-08-21 | PXD035143 | Pride
Gene expression profiles of "spontaneous" and transplanted topotecan-resistant BRCA1;P53-deficient mammary tumors and their matched untreated controls
ORGANISM(S): Mus musculus 
One major class of anti-cancer drugs targets topoisomerase II to induce DNA double-strand breaks and cell death of fast growing cells. In vitro experiments showed that doxorubicin can induce histone eviction as well as DNA damage, while etoposide can only induce DNA damage. Here, we compare the tran...
ORGANISM(S): Mus musculus 
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