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ProteomicsA noncanonical role of roX RNAs in autosomal epigenetic repression
Long noncoding RNAs known as roX (RNA on X) are crucial for male development in Drosophila, as their loss leads to male lethality from the late larval stages. While roX RNAs are recognized for their role in sex-chromosome dosage compensation, ensuring balanced expression of X-linked genes in both se...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-11-14 | PXD047183 | Pride
Chirp-ms Polycomb repressive complexes Long noncoding rnas Rox 
TranscriptomicsTranscription profiling of Drosophila male third instar larva y+ w roX1- roX2-/y vs y+ w roX1+ roX2-/y reveals roX RNAs are required for increased expression of X-linked genes in Drosophila melanogaster males
Drosophila males double transcription of their single X chromosome to equalize X-linked gene expression with females, which carry two X chromosomes. Increased transcription requires the Male-Specific Lethal (MSL) complex. One of the primary functions of the MSL complex is thought to be enrichment ...
ORGANISM(S): Drosophila melanogaster 
2008-03-13 | E-GEOD-3990 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila females reveals roX RNAs are not required for expressional regulation in Drosophila females
roX RNAs are involved in the chromosome-wide gene regulation that occurs during dosage compensation in Drosophila. Dosage compensation equalizes expression of X-linked and autosomal genes. Drosophila males increase transcription two-fold from their single X chromosome. This is mediated by the MSL co...
ORGANISM(S): Drosophila melanogaster 
2009-08-08 | E-GEOD-12076 | biostudies-arrayexpress
GenomicsA noncanonical role of roX RNAs in autosomal epigenetic repression [RNA-seq]
A noncanonical role of roX RNAs in autosomal epigenetic repression [RNA-seq]
PRJNA1045627 | ENA
GenomicsA noncanonical role of roX RNAs in autosomal epigenetic repression [ChIP-seq]
A noncanonical role of roX RNAs in autosomal epigenetic repression [ChIP-seq]
PRJNA1045625 | ENA
GenomicsA noncanonical role of roX RNAs in autosomal epigenetic repression [PIRCh-seq]
A noncanonical role of roX RNAs in autosomal epigenetic repression [PIRCh-seq]
PRJNA1045626 | ENA
GenomicsroX ChIRP-seq in four Drosophila species
roX ChIRP-seq in four Drosophila species
PRJNA284887 | ENA
TranscriptomicsA noncanonical role of roX RNAs in autosomal epigenetic repression [RNA-seq]
Long noncoding RNAs known as roX (RNA on X) are crucial for male development in Drosophila, as their loss leads to male lethality from the late larval stages. While roX RNAs are recognized for their role in sex-chromosome dosage compensation, ensuring balanced expression of X-linked genes in both se...
ORGANISM(S): Drosophila melanogaster 
2024-11-19 | GSE248700 | GEO
OtherA noncanonical role of roX RNAs in autosomal epigenetic repression [PIRCh-seq]
Long noncoding RNAs known as roX (RNA on X) are crucial for male development in Drosophila, as their loss leads to male lethality from the late larval stages. While roX RNAs are recognized for their role in sex-chromosome dosage compensation, ensuring balanced expression of X-linked genes in both se...
ORGANISM(S): Drosophila melanogaster 
2024-11-19 | GSE248699 | GEO
GenomicsA noncanonical role of roX RNAs in autosomal epigenetic repression [ChIP-seq]
Long noncoding RNAs known as roX (RNA on X) are crucial for male development in Drosophila, as their loss leads to male lethality from the late larval stages. While roX RNAs are recognized for their role in sex-chromosome dosage compensation, ensuring balanced expression of X-linked genes in both se...
ORGANISM(S): Drosophila melanogaster 
2024-11-19 | GSE248698 | GEO
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