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Mutant KRAS (mut-KRAS) is present in 30% of all human cancers and plays a critical role in cancer cell growth and resistance to therapy. There is evidence from colon cancer that mut-KRAS is a poor prognostic factor and negative predictor of patient response to molecularly targeted therapy. However,...
ORGANISM(S): Homo sapiens 
Epithelial/mesenchymal transition (EMT) is associated with loss of cell adhesion molecules, such as E-cadherin, and increased invasion, migration, and proliferation in epithelial cancers. In non-small cell lung cancer (NSCLC), EMT is associated with greater resistance to EGFR inhibitors. However, it...
ORGANISM(S): Homo sapiens 
Comparative Proteomics of the Secretory/Excretory products (SEPs) of 2 life stages L.salmonisusing LC-ESI-MS/MS.
ORGANISM(S): Lepeophtheirus salmonis 
2018-10-19 | PXD009391 | Pride
Purpose: To determine the 8-week disease control rate (DCR) of sorafenib monotherapy in patients with advanced non-small-cell lung cancer (NSCLC) in the BATTLE trial. Methods: Patients with pre-treated NSCLC consented to baseline biopsies for pre-specified biomarkers assessment and biomarker discove...
ORGANISM(S): Homo sapiens 
abundance based on iBAQ, Interaction consistency score: 14.8, Coverage: 27
ORGANISM(S): 3880 
2016-00-00 | 2164794630 | PAXDB
abundance based on iBAQ, Interaction consistency score: 13.0, Coverage: 29
ORGANISM(S): 3880 
2016-00-00 | 3047189613 | PAXDB
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